Molecular Machines in Biology

ISBN-13: 9780521194280 / Angielski / Twarda / 2011 / 288 str.

Joachim Frank

Opis

Discusses molecular machines and new techniques that are being used to better understand the processes in the cell driven by them.

Recenzje

'… insightful language about molecular machines …' Evolution News and Views

Spis treści

Introduction; 1. Single-molecule FRET: technique and applications to the studies of molecular machines Xinghua Shi and Taekjip Ha; 2. Visualization of molecular machines by cryo-electron microscopy Joachim Frank; 3. Statistical mechanical treatment of molecular machines Debashish Chowdhury; 4. Investigation of molecular machines by normal mode analysis Karunesh Arora and Charles L. Brooks, III; 5. Structure, function, and evolution of archaeo-eukaryotic RNA polymerases - gatekeepers of the genome Finn Werner and Dina Grohmann; 6. Single-molecule fluorescence resonance energy transfer investigations of ribosome-catalyzed protein synthesis Daniel D. MacDougall, Jingyi Fei and Ruben L. Gonzalez, Jr; 7. Structure and dynamics of the ribosome as revealed by cryo-electron microscopy Xabier Agirrezabala and Mikel Valle; 8. Viewing the mechanisms of translation through the computational microscope James Gumbart, Eduard Schreiner, Leonardo G. Trabuco, Kwok-Yan Chan and Klaus Schulten; 9. The ribosome as a Brownian ratchet machine Alexander S. Spirin and Alexei V. Finkelstein; 10. The GroEL/GroES chaperonin machine Arthur L. Horwich and Helen R. Saibil; 11. ATP synthase - a paradigmatic molecular machine Thomas Meier, José Faraldo-Gómez and Michael Börsch; 12. ATP-dependent proteases Sucharita Bhattacharyya, Shameika R. Wilmington and Andreas Matouschek.