Philosophy of Molecular Medicine: Foundational Issues in Research and Practice

ISBN-13: 9780367736699 / Angielski / Miękka / 2020 / 288 str.

Giovanni Boniolo; Marco J. Nathan

Opis

Despite its prominence in scientific research, molecular medicine has not received sufficient attention by the philosophical community. Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organiz

Recenzje

Philosophy of Molecular Medicine offers 12 insightful chapters of philosophical and historical reflections on foundational issues in molecular medicine. This edited volume offers a rich introduction to and discussion of important philosophical issues that arise at the interface of basic science, clinical research, and clinical practice.
-Sara Green, Springer

Spis treści

Introduction

Giovanni Boniolo and Marco J. Nathan

　

Part 1: Nature, Origins, and Scope

Chap. 1: Molecular medicine: the clinical method enters the lab. What tumor heterogeneity and primary tumor culture teach us

Giovanni Boniolo

Chap. 2: Personalized Medicine: Historical Roots of a Medical Model

Mariacarla Gadebusch Bondio and Francesco Spöring

Chap. 3: From the concept of genetic disease to the geneticization of diseases: analyzing and solving the paradox of contemporary medical genetics

Marie Darrason

　

Part 2: Explanation

Chap. 4: Molecular complexity: Why has psychiatry not been revolutionized by genomics (yet)?

Maël Lemoine

Chap. 5: How cancer spreads: reconceptualizing a disease

Katherine E. Liu, Alan C. Love, and Michael Travisano

Chap. 6: Evolutionary Perspectives on Molecular Medicine: Cancer from an Evolutionary Perspective

Anya Plutynski

　

Part 3: Representation and Modeling

Chap. 7: Towards a Notion of Intervention in Big-Data Biology and Molecular Medicine

Federico Boem and Emanuele Ratti

Chap. 8: Pathways to the clinic: cancer stem cells and challenges for translational research

Melinda Bonnie Fagan

Chap. 9: Counterfactual Reasoning in Molecular Medicine

Marco J. Nathan

　

Part 4: Inference

Chap. 10: Forms of Extrapolation in Molecular Medicine

Pierre-Luc Germain and Tudor Baetu

Chap. 11: Testing Oncological Treatments in the Era of Personalized Medicine

David Teira

Chap. 12: Opportunities and challenges of molecular epidemiology

Federica Russo and Paolo Vineis

O autorze

Giovanni Boniolo (degrees in Physics and in Philosophy) is Professor of Philosophy of Science and Medical Humanities at the Università di Ferrara, and Anna Boyksen Fellow at the Institute for Advanced Study, Technische Universität München. He has published 13 books (plus 12 books edited) and about 200 research articles.

Marco J. Nathan is Assistant Professor of Philosophy at the University of Denver. His work has been published in various philosophical and scientific venues, including Noûs, Philosophy of Science, British Journal for Philosophy of Science, Nephrology Dialysis and Transplantation, Biology and Philosophy, and Synthese.