1. Biostimulants: An Introduction 2. Sources of endogenous biostimulants in plants 3. Role of Biostimulants in plant's life cycle 4. Biostimulants homeostasis in plants 5. Implication of endogenous biostimulants in regulating Cd toxicity 6. Implication of endogenous biostimulants in regulating As toxicity 7. Implication of endogenous biostimulants in regulating Al toxicity 8. Exogenous application of biostimulants and Cd stress tolerance 9. Exogenous application of biostimulants and As stress tolerance 10. Exogenous application of NO and Al stress tolerance 11. Exogenous application of Biostimulants and commercial utilization 12. Biostimulants and regulation of Cr, Pb, Fe, Zn, Hg, Cu, Mn and Ni stress in plants 13. Biostimulants signalling under Cd, Al, As, Zn, Fe toxicity 14. Post translational modifications and metal stress tolerance in plants 15. Adventitious root formation and Biostimulants under metal stress 16. Crosstalk of biostimulants with other signalling molecules under metal stress 17. Biotechnological attributes of biostimulants for relieving metal toxicity Heavy metal stress and biostimulants interaction: Conclusion and future perspectives