1. Methods for Studying Nucleic Acid Structure 2. The Building-Blocks of DNA and RNA 3. DNA Structure as Observed in Fibers and Crystals 4. Non-standard and Higher-Order DNA Structures: DNA-DNA Recognition 5. Principles of Small Molecule-DNA Recognition 6. RNA Structures and Their Diversity 7. Principles of Protein-DNA Recognition 8. RNA Binding Proteins