5-Ht4 Receptors in the Brain and Periphery

ISBN-13: 9783540641643 / Angielski / Twarda / 1998 / 229 str.

Richard M. Eglen; R. M. Eglen

Opis

The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function. With chapters written by specialists in the field, this is a comprehensive review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors.

Spis treści

1. Medicinal Chemistry of 5-HT4 Receptor Ligands.- 2. Molecular Biology of 5-HT4 Receptors.- 3. Localization of 5-HT4 Receptors in Vertebrate Brain and Their Potential Behavioral Roles.- 4. Central 5-HT4 Receptors: Electrophysiology.- 5. Neurochemical Consequences Following Pharmacological Manipulation of Central 5-HT4 Receptors.- 6. 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors.- 7. 5-HT4 Receptors in Gastrointestinal Tract.- 8. 5-HT4 Receptors in Lower Urinary Tract Tissues.- 9. The 5-HT4 Receptor in the Adrenal Gland.- 10. Therapeutic Applications of 5-HT4 Receptor Agonists and Antagonists.