3D DNA Nanostructure: Methods and Protocols

ISBN-13: 9781493982059 / Angielski / Miękka / 2018 / 282 str.

Yonggang Ke; Pengfei Wang

Spis treści

Part I: DNA/RNA Structure Design

 

1. Designed 3D DNA Crystals

            Nadrian C. Seeman, Ruojie Sha, Jens Birktoft, Jianping Zheng, Wenyan Liu, Tong Wang, and Chengde Mao

 

2. Three-Dimensional DNA Nanostructures Assembled from DNA Star Motifs

            Cheng Tian and Chuan Zhang

 

3. Design of Wireframe DNA Nanostructures-DNA Gridiron

            Dongran Han

 

4. Complex DNA Brick Assembly

            Luvena Ong, Yonggang Ke, and Peng Yin

 

5. Computer-Aided Design of RNA Origami Structures

            Steffen L. Sparvath, Cody W. Geary, and Ebbe S. Andersen

 

6. Assembling RNA Nanoparticles

            Shou-Jun Xiao

 

Part II: Applications of DNA Structures

 

7. DNA Functionalization of Nanoparticles

            Fang Lu and Oleg Gang

 

8. Purification Techniques for Three-Dimensional DNA Nanostructures

            Travis A. Meyer

 

9. DNA Nanostructure as Smart Carriers for Drug Delivery

            Xiangyuan Ouyang, Jie Chao, Shao Su, and Chunhai Fan

 

10. DNA G-Quadruplex-Based Assay of Enzyme Activity

            Zhuoliang Liu, Kaiyu He, Wang Li, Xin Liu, Xiahong Xu, Zhou Nie, and Shouzhuo Yao

 

11. Assembly of Multi-Enzyme Cascade on a DNA Origami Nanostructure

            Jinglin Fu and Tianran Li

 

12. Lipid Membrane Encapsulation of a 3D DNA NanoOctahedron

            Steven D. Perrault and William M. Shih

 

13. DNA-PAINT Super-Resolution Imaging for Nucleic Acid Nanostructures

            Mingjie Dai

 

14. Designing DNA Nanotube Liquid Crystals as a Weak-Alignment Medium for NMR Structure Determination of Membrane Proteins

            John Min, William M. Shih, and Gaëtan Bellot

 

15. Direct Nanofabrication Using DNA Nanostructure

            Feng Zhou and Haitao Liu

 

16. Confined Growth of Metal Nanoparticles Within 3D DNA Origami Molds

            Wei Sun and Jie Shen

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17. DNA-Directed Self-Assembly of Highly Ordered and Dense Single Walled Carbon Nanotube Arrays

            Hareem Maune and Si-ping Han

 

18. A Proximity-Based Programmable DNA Nanoscale Assembly Line

            Xiaoyan Zhang, Xiaoqiang Ding, Jianzhou Zou, and Hongzhou Gu

 

19. DNA Walkers as Transport Vehicles of Nanoparticles Along a Carbon Nanotube Track

            Jing Pan, Tae-Gon Cha, Haorong Chen, Feiran Li, and Jong Hyun Choi

Blurb

This detailed volume presents a comprehensive technical overview of DNA nanotechnology with an emphasis on 3D DNA nanostructure design and applications. Coverage spans from basic design principles for DNA and RNA nanostructures to their cutting-edge applications in a variety of fields, with the book divided into basic DNA and RNA nanostructure design strategies as well as applications utilizing DNA nanostructures, including but not limited to nanomedicine, bioimaging, biosensing, nanoplasmonics, nanoelectronics, nanofabrication, crystallography, biophysics, and analytical chemistry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Comprehensive and authoritative, 3D DNA Nanostructure: Methods and Protocols provides the most up-to-date tutorial style overviews and technical style protocols to benefit researchers in a wide variety of areas.