Contributors viiAcknowledgments xiAbbreviations xiii1 Introduction 12 Development of knowledge about cerebrovascular disease 7Jan van Gijn3 Is it a vascular event and where is the lesion? 37Simon Jung and Heinrich P. Mattle4 Which arterial territory is involved? 129John C.M. Brust5 What is the role of imaging in acute stroke? 1715A Neuroimaging 172Marwan El-Koussy5B Ultrasound of the extra- and intracranial arteries 224Georgios Tsivgoulis and Apostolos Safouris5C Cardioembolic stroke 241Issam Mikati and Zeina Ibrahim6 What caused this transient or persisting ischemic event? 267Fernando D. Testai7 Unusual causes of ischemic stroke and transient ischemic attack 345Fan Z. Caprio and Chen Lin8 What caused this intracerebral hemorrhage? 399Farid Radmanesh and Jonathan Rosand9 What caused this subarachnoid hemorrhage? 437Matthew B. Maas and Andrew M. Naidech10 A practical approach to the management of stroke and transient ischemic attack 455H. Bart van der Worp and Martin Dennis11 What are this patient's problems? A problem-based approach to the general management of stroke 481Yannie Soo, Howan Leung, and Lawrence Ka Sing Wong12 Have the patient's cognitive abilities been affected? 579Leonardo Pantoni13 Specific treatment of acute ischemic stroke 587Eivind Berge and Peter Sandercock14 Specific treatment of intracerebral hemorrhage 657Shoichiro Sato and Craig S. Anderson15 Specific treatment of aneurysmal subarachnoid hemorrhage 679Gregory Arnone and Sepideh Amin-Hanjani16 Specific interventions to prevent intracranial hemorrhage 723Preston W. Douglas, Clio A. RubiDos, and Sean Ruland17 Preventing recurrent stroke and other serious vascular events 745Cathra Halabi, Rene Colorado, and Karl Meisel18 Rehabilitation after stroke: evidence, practice, and new directions 867Coralie English, Audrey Bowen, Debbie Hébert, and Julie Bernhardt19 The organization of stroke services 879Peter Langhorne, Jeyaraj Durai Pandian, and Cynthia Felix20 Reducing the impact of stroke and improving public health 933Graeme J. Hankey and Philip B. GorelickIndex 953
The EditorsGraeme J. Hankey MBBS, MD, FRACP, FRCPE, FAHA, FESO, FAAHMS, Professor of Neurology, Medical School, The University of Western Australia, Perth, Australia; and Consultant Neurologist, Sir Charles Gairdner Hospital, Perth, Western AustraliaMalcolm Macleod BSc(Hons), MBChB, PhD, FRCP, Professor of Neurology and Translational Neurosciences at the University of Edinburgh, and Honorary Consultant Neurologist and Head of Neurology, NHS Forth Valley, UKPhilip B. Gorelick MD, MPH, FACP, FAHA, FAAN, FANA, Professor Translational Science and Molecular Medicine at Michigan State University, Grand Rapids, MI, USA; and Adjunct Professor, Davee Department of Neurology, Northwestern Feinberg School of Medicine, Chicago, IL, USA; and International Fellow, Population Health Research Institute affiliated with McMaster University Faculty of Health Sciences and Hamilton Health Sciences, Hamilton, ON, Canada; and Professor Emeritus, Department of Neurology and Rehabilitation, University of Illinois College of Medicine, Chicago, IL, USAChristopher Chen BA, BMBCh, FRCP, Director, Memory Aging & Cognition Centre, National University Health System, Singapore; and Associate Professor, Department of Pharmacology, National University of Singapore, Singapore; and Senior Consultant Neurologist, Department of Psychological Medicine, National University Hospital, SingaporeFan Z. Caprio MD, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USAHeinrich Mattle MD, FRCPE, FAHA, FESO, Professor, Senior Consultant, Department of Neurology, University of Bern, Bern, Switzerland