T-Cell Lymphomas

ISBN-13: 9781627031691 / Angielski / Twarda / 2012 / 340 str.

Francine Foss

Opis

The mature T and NK cell lymphomas are rare, comprising approximately 10% of all malignant lymphomas. The incidence of T-cell lymphoma is variable around the world, with a higher incidence compared to B-cell lymphomas in the Asian basin. While the overall incidence of B-cell lymphomas has begun to decline in the United States, the incidence of T-cell lymphomas continues to rise. Over the last decade, a number of novel agents have been developed which target T-cell lymphomas and studies have identified novel genes and pathways associated with lymphomagenesis in T-cells. This comprehensive volume examines the clinical and biological aspects of the T-cell lymphoproliferative disorders in adults and children. The book includes an overview of both the cutaneous and the systemic T-cell malignancies and addresses the classification of T-cell lymphomas, the clinical features of each subtype, and the relevant molecular and genetic studies. Clinical outcomes and treatment strategies are discussed with an emphasis on the development of novel biological and targeted therapies. An outstanding resource for hematologists and oncologists, this book gathers insights from experts in the field and provides the most up-to-date information on all of the T-cell lymphoma subgroups and current and emerging therapies.

Recenzje

From the reviews:

"This is a thorough review of the current knowledge about T-cell lymphomas, from basic science to clinical aspects. ... The purpose is to thoroughly review the sum of knowledge of this set of diseases, one which has been met well. The book is most appropriate for residents, oncology/hematology fellows, and practicing oncologists, and can be a good reference for those who specialize in hematologic malignancies." (Adam M. Petrich, Doody's Book Reviews, September, 2013)

Spis treści

1. Classification of the T-cell lymphomas
2. Epidemiology, prognosis and outcomes for aggressive T-cell lymphomas –
3. Molecular pathogenesis of T-cell lymphoma-
4. HTLV-1 associated T-cell diseases-
5. The NK/T cell lymphomas-
6. CD30 positive T-cell lymphomas-
7. Extranodal T-cell lymphomas
8. Nodal T-cell lymphomas
9. The T-cell leukemias
10. Chemotherapy and Bone Marrow Transplantation
11. Antibodies and Targeted Therapies
12. Novel agents for T-cell lymphomas
13. Immune Therapies in T-cell lymphoma