Spinal anesthesia, and opioid additives

ISBN-13: 9783659550621 / Angielski / Miękka / 2014 / 68 str.

Goma Hala

Opis

Spinal anesthesia provides adequate anesthesia plus postoperative analgesia lead to reduction requirements of systemic opioids resulting in avoidance of sedation and respiratory depression. More importantly, the inhibition of the stress response to surgery, trauma induced nociceptive impulses, and blunting of the autonomic and somatic responses to pain facilitate breathing, coughing, sighing and early ambulation . This results in restoration of pulmonary function and reduction of post operative chest infection and pulmonary collapse. Finally, efferent sympathetic blockade results in increased blood flow to the region of neural blockade resulting in better wound healing and reduced risk of deep venous thrombosis and thromboembolism Opioid receptors are dicovered in the dorsal horn and the brainstem. Binding of opioid receptors causes hyperpolarization of nerve membranes, which decreases nerve impulse transmission.

O autorze

Hala M Goma : MD ,professor of anesthesia Cairo university Coauthor of Diagnostic Techniques and Surgical Management of Brain Tumors Copyright © 2011 InTech.Coauthor of Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain TumorsPublished April, 2013.