Prader-Willi Syndrome: Development and Manifestations

ISBN-13: 9780521840293 / Angielski / Twarda / 2004 / 232 str.

Joyce Whittington; Tony Holland; Joyce Whittington

Opis

Prader-Willi Syndrome (PWS) is associated with an assortment of physical, behavioral and cognitive abnormalities that create a broad range of interdisciplinary care needs. Joyce Whittington and Tony Holland identify and integrate the latest findings on managing the complex medical, nutritional, psychological, educational, social and therapeutic needs of people with PWS. Both have been involved in the Cambridge PWS study--the largest of the cohort studies of PWS--which provides the basis of this book.

Recenzje

Review of the hardback: '… provides a wealth of very valuable facts to add to the jigsaw pieces that will eventually reveal a whole picture of a fascinating syndrome.' European Journal of Paediatric Neurology

Spis treści

Introduction; Part I. Background: PWS, Why, What, and How To Investigate: 1. Background and historical overview; 2. Biological and regulatory mechanisms in PWS; 3. The Cambridge PWS project; Part II. PWS Prevalence, Phenotypic Functioning and Characteristics: 4. Prevalence, birth incidence and mortality; 5. Relationship between genetic and clinical diagnosis; 6. Phenotypic differences between the genetic subtypes; 7. Cognitive function and attainments; 8. The behavioural phenotype of PWS; 9. Medical conditions affecting people with PWS; 10. Psychiatric illness; 11. Obsessions and compulsions; Part III. Minor Findings, Some Conclusions and Future Directions: 12. Understanding PWS; Index.