Peptidomimetics I

ISBN-13: 9783319491172 / Angielski / Twarda / 2018 / 310 str.

William Lubell

Opis

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community.

Spis treści

4-Fluoroprolines: Conformational Analysis and Effects on the Stability and Folding of Peptides and Proteins .- Silaproline, a silicon-containing proline surrogate .- Proline Methanologues – Design, Synthesis, Structural Properties, and Applications in Medicinal Chemistry.- Structure and Synthesis of Conformationally Constrained Molecules Containing Piperazic Acid.- Aminolactam, N-aminoimidazolone and N-aminoimdazolidinone peptide mimics.- Azepinone-Constrained Amino Acids in Peptide and Peptidomimetic Design.- Polyhydroxylated cyclic delta amino acids: Synthesis and conformational influences on biopolymers.- Thiazoles in Peptides and Peptidomimetics.- Advances in Merging Triazoles with Peptides and Proteins.