miRNomics: MicroRNA Biology and Computational Analysis

ISBN-13: 9781071611722 / Angielski / Miękka / 2021

Allmer, Jens

Opis

This second edition presents an up-to-date overview of the current state-of-the-art protocols and aims to miRNomics into a broader perspective. Chapters detail methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, miRNomics: MicroRNA Biology and Computational Analysis, Second Edition ensures successful results in the further study of this vital field.

Spis treści

1           Regulation of MicroRNAs

Kemal Ergin and Rahmi Çetinkaya

 

2           Experimental MicroRNA Detection Methods

Bilge Yaylak and Bünyamin Akgül

 

3           Functional Annotation of MicroRNAs using Existing Resources

Harsh Dweep, Louise C. Showe, and Andrew V. Kossenkov

 

4           Experimental MicroRNA Targeting Validation

Bala Gür Dedeoğlu and Senem Noyan

 

5           Endogenous miRNA Sponges

Ayşe Hale Alkan and Bünyamin Akgül

 

6           MicroRNA Targeting

Hossein Ghanbarian, Mehmet Taha Yıldız, and  Yusuf Tutar

 

7           MicroRNA Databases and Tools

Tharcísio Soares de Amorim, Daniel Longhi Fernandes Pedro, and Alexandre Rossi Paschoal

 

8           Computational Detection of Pre-microRNAs

Müşerref Duygu Saçar Demirci

 

9           Computational Methods for Predicting Mature MicroRNAs

Malik Yousef, Alisha Parveen, and Abhishek Kumar

 

10       Computational Detection of MicroRNA Targets

Pedro Gabriel Nachtigall and Luiz Augusto Bovolenta

 

11       Evolution and Phylogeny of MicroRNAs --- Protocols, Pitfalls, and Problems

Cristian A. Velandia-Huerto, Ali M. Yazbeck, Jana Schor, and  Peter F. Stadler

 

12       Ensemble Classifiers for Multi-class MicroRNA Classification

Luise Odenthal, Jens Allmer, and Malik Yousef

 

13       MicroRNAs in Genetic Etiology of Human Diseases

Melis Olcum, Kemal Ugur Tufekci, and Sermin Genc

 

14       The role of Exosomal MicroRNAs in Cell-to-Cell Communication

Bora Tastan, Emre Tarakcioglu, Yelda Birinci, Yongsoo Park, and Sermin Genc

 

15       MicroRNAs and Heat Shock Proteins in Breast Cancer Biology Mehmet Taha Yıldız, Lütfi Tutar, Nazlı Irmak Giritlioğlu, Banu Bayram and Yusuf Tutar

 

16       Role of MicroRNAs in Extreme Animal Survival Strategies

Hanane Hadj-Moussa, Liam J. Hawkins, and Kenneth B. Storey

 

17       Computational and Bioinformatics Methods for MicroRNA Gene Prediction

Ege Riza Karagur, Sakir Akgun, and Hakan Akca

18       The Role of MiRNA in Cancer: Pathogenesis, Diagnosis, and Treatment

Erez Uzuner, Gizem Tugçe Ulu, Sevim Beyza Gürler, and Yusuf Baran

 

19        Current Challenges in miRNomics Bünyamin Akgül, Peter F Stadler, Liam J Hawkins, Hanane Hadj-Moussa, Kenneth B Storey, Kemal Ergin, Rahmi Çetinkaya, Alexandre R Paschoal, Pedro G Nachtigall, Yusuf Tutar, Malik Yousef, and Allmer Jens

Blurb

This second edition presents an up-to-date overview of the current state-of-the-art protocols and aims to put the miRNomics into a broader perspective. Chapters detail methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, the miRNomics second edition chapters include introductions to their respective topics, application details for both the expert and non-expert reader and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and accessible, miRNomics: MicroRNA Biology and Computational Analysis, Second Edition ensures successful results in the further study of this vital field.