Kategoria BISAC: Science >> Bioinformatics

This book constitutes the refereed proceedings of the Third International Symposium on Bioinformatics Research and Applications, ISBRA 2007, held in Atlanta, GA, USA in May 2007. The 55 revised full papers presented together with three invited talks cover a wide range of topics, including clustering and classification, gene expression analysis, gene networks, genome analysis, motif finding, pathways, protein structure prediction, protein domain interactions, phylogenetics, and software tools.

This book presents applications of bioinformatics tools that experimental research scientists use in "daily practice." Its interdisciplinary approach combines computational and experimental methods to solve scientific problems. The book begins with reviews of computational methods for protein sequence-structure-function analysis, followed by methods that use experimental data obtained in the laboratory to improve functional predictions.

This book defines the field of systems biology, one of the newest and fastest developing fields in science today. It discusses the most effective experimental and computational strategies and highlights new and emerging applications. Cell biologists and other readers will discover many benefits for industry, such as the new network-based drug-target design validation. The authors also thoroughly explore testing.

Sir Francis Crick would undoubtedly be at the front of the line ordering this fascinating book. Being one of the discoverers of DNA, he would be amazed at how his work has been applied to mankind's most important invention, the computer. DNA contains the genetic instructions for the biological development of cellular life forms or viruses. DNA computing uses DNA as a substrate for storing information, while molecular biological operations are used to manipulate this information.

DNA Computing Models begins with a comprehensive introduction to the field of DNA computing. This book...

An Easy-to-Use Research Tool for Algorithm Testing and Development

Before the SeqAn project, there was clearly a lack of available implementations in sequence analysis, even for standard tasks. Implementations of needed algorithmic components were either unavailable or hard to access in third-party monolithic software products. Addressing these concerns, the developers of SeqAn created a comprehensive, easy-to-use, open source C++ library of efficient algorithms and data structures for the analysis of biological sequences. Written by the founders of this project, Biological...

The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse data on protein-protein interactions and protein interaction networks.

Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and...

Suitable for advanced undergraduates and postgraduates, Understanding Bioinformatics provides a definitive guide to this vibrant and evolving discipline. The book takes a conceptual approach. It guides the reader from first principles through to an understanding of the computational techniques and the key algorithms. Understanding Bioinformatics is an invaluable companion for students from their first encounter with the subject through to more advanced studies.

The book is divided into seven parts, with the opening part introducing the basics of nucleic acids,...

Biomechanics studies of animals in swimming and flying can serve an increasing role in understanding the mechanisms that enable animals to move effectively and efficiently in fluid, as well as analyzing the characteristics of their various forms of behavior in fluid. The rich variety of mechanisms employed by swimming and flying organisms has long been an inspiration for engineers and scientists. These areas of research, which form the basis of this volume, include the locomotive mechanisms and behaviors of animals in swimming and flying ranging from microorganisms to dolphins from the...

Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume II: Structure, Function and Applications contains methods pertinent to the...

There are fundamental principles for problem analysis and algorithm design that are continuously used in bioinformatics. This book concentrates on a clear presentation of these principles, presenting them in a self-contained, mathematically clear and precise manner, and illustrating them with lots of case studies from main fields of bioinformatics (e.g. sequencing and mapping, string storage and manipulation, pattern matching, alignment, gene identification, genome rearrangement, structure prediction, regulatory networks, pseudoknot detection). Emphasis is laid on algorithmic "pearls" of...