Kategoria BISAC: Science >> Life Sciences - Anatomy & Physiology

This second edition provides new and updated methods and techniques for identification of drug target, binding sites prediction, high- throughput virtual screening, lead discovery and optimization, conformational sampling, prediction of pharmacokinetic properties using computer-based methodologies. Chapters also focus on the application of the latest artificial intelligence technologies for computer aided drug discovery. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists...

This volume offers the latest research-based findings to equip professionals involved in the breeding and raising of horses. Contributions were carefully selected and prepared by leading experts in their fields. The collection starts with a discussion of pregnant and lactating mares, followed by details on foal development, nutritional requirements, and feeding practices under different conditions. Special sections on young horses in training, parasite control as well as on health risks related to nutrition and exercise round off this unique and easy-to-read reference.

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This third edition details new and updated methods and protocols on important databases and data mining tools. Chapters guides readers through archives of macromolecular sequences and three-dimensional structures, databases of protein-protein interactions, methods for prediction conformational disorder, mutant thermodynamic stability, aggregation, and drug response. Quality of structural data and their release, soft mechanics applications in biology, and protein flexibility are considered, too, together with pan-genome analyses, rational drug combination screening and Omics Deep Mining....