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Restriction Landmark Genomic Scanning (Rlgs)
ISBN: 9784431685210 / Angielski / Miękka / 179 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Restriction Landmark Genomic Scanning (RLGS) is a new multiplex method for simultaneous analysis of over 3,000 genome loci. Written by the inventor of RLGS, Yoshihide Hayashizaki, and his co-workers, this is the first manual on this method. RLGS is a powerful technique with enormous potential for biological (animal and plant sciences), and biomedical research. Yielding results much faster than conventional techniques, RLGS is particularly suited to the identification of the chromosomal location of the genes implicated in inherited diseases, and for the genetic disturbances present in...
Restriction Landmark Genomic Scanning (RLGS) is a new multiplex method for simultaneous analysis of over 3,000 genome loci. Written by the inventor of...
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cena:
203,61 |
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Nuclear Factor кb: Regulation and Role in Disease
ISBN: 9789401039833 / Angielski / Miękka / 426 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-kappaB is central to a number of cellular functions including cell proliferation, apoptosis, and cellular differentiation. This transcription factor also plays essential roles in innate and acquired immunity, and its deregulation leads to important human diseases such as inflammation and cancer. Therefore NF-kappaB, together with the signaling pathways leading to its activation, constitute an attractive therapeutic target. This book is the first...
The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-k...
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cena:
470,56 |
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Spermatogenesis Genetic Aspects
ISBN: 9783662224236 / Angielski / Miękka / 130 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Spermatogenesis is one of the fundamental but at the same time also one of the most complex differentiation processes in higher eukaryotes. For a long time the development of spermatozoa has been considered as related solely to the needs of transfer of the paternal genome into the egg. Other paternal contributions to the development of the embryo were not seriously considered. Only recently has it become evident, from studies of mouse embryonic development by Solter and colleagues, that also the paternal genome carries regulatory information into the zygote since the development of a mouse...
Spermatogenesis is one of the fundamental but at the same time also one of the most complex differentiation processes in higher eukaryotes. For a long...
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cena:
541,33 |
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Die Extracutanen Melanocyten Der Echsen (Sauria)
ISBN: 9783662241585 / Niemiecki / Miękka / 55 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Knochenfische, Amphibien und Reptilien besitzen in ausgedehntem Masse extracutane Pigmentierungen. Bei diesen niederen Vertebraten kommen Pigment zellen nicht nur in der Epidermis und reich ausgebildet im Corium vor, sondern auch an vielen Organen des Korperinneren, in teilweise weiter Ausdehnung. So sind die Dura mater und die Leptomeninx, das parietale Peritonaeum und die Mesenterien, Gefasse undN erven, der Darm und die Keimdrusen, dasfettspeichernde Bindegewebe, das Periost und das Knochenmark mit Chromatophoren versehen, und zwar in jeweils spezifischer Auswahl der pigmentierten...
Knochenfische, Amphibien und Reptilien besitzen in ausgedehntem Masse extracutane Pigmentierungen. Bei diesen niederen Vertebraten kommen Pigment zell...
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cena:
209,31 |
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Molecular Approaches to Supracellular Phenomena
ISBN: 9780812282511 / Angielski / Twarda / 242 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume focuses on a group of diverse developmental processes that have resisted incisive analysis when conventional genetic and biochemical methodologies were employed. Relatively little is known at the molecular level about these processes, but the contributors have taken a firm stand by either presenting hypotheses or suggesting new ways to approach research problems in their fields. The authors describe new models and hypotheses for such complex questions as: Embryos are biological clocks, but how do they keep time? Oncogenes cause many tumors, even though they are, or are... This volume focuses on a group of diverse developmental processes that have resisted incisive analysis when conventional genetic and biochemical me... |
cena:
377,54 |
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Stem Cells and Cancer Stem Cells, Volume 1: Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 1
ISBN: 9789400738270 / Angielski / Miękka / 200 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of human pluripotent stem cells, mesenchymal stem cells, and hematopoietic stem cells in cancer therapy and tissue/organ regeneration is detailed. Role of neural cancer stem cells in brain tumors, including their role in brain tumor therapy and the role of CD133 stem cell antigen in glioma patients, is emphasized. Therapeutic role of bone marrow-derived stem cells in myocardial infarction and the role of mesenchymal stem cells in orthopedics are...
Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of hum...
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cena:
814,55 |
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Stem Cells and Cancer Stem Cells, Volume 2: Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 2
ISBN: 9789400738287 / Angielski / Miękka / 384 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As in volume 1 of this series, this volume presents information on stem cells and cancer stem cells; Therapeutic Applications in disease and tissue/organ injury. Methodologies of regenerative medicine and tissue engineering are major components of this volume. Specific stem cells discussed are: human embryonic stem cells, hematopoietic stem cells, cord blood stem cells, human pluripotent stem cells, gliosarcoma stem cells, induced pluripotent stem cells, intestinal stem cells, human thyroid cancer stem cells, tumor stem cells, menstrual stem-like cells, neural stem cells, breast cancer stem...
As in volume 1 of this series, this volume presents information on stem cells and cancer stem cells; Therapeutic Applications in disease and tissue/or...
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cena:
814,55 |
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Advances in Immunology: Volume 121
ISBN: 9780128001004 / Angielski / Twarda / 276 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in...
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cena:
665,65 |
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Cell-Based Microarrays: Review of Applications, Developments and Technological Advances
ISBN: 9781493905935 / Angielski / Miękka / 100 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is a review on the evolution of cell-based microarrays and an update to the author's earlier book Methods in Molecular Biology: Cell-Based Microarrays. Since their development in 2001, cell-based microarrays have advanced signi cantly to include expression arrays, short interfering RNA arrays and antibody arrays. The surface used to coat the glass slides has also been significantly improved to allow non-adherent cells to bind to the arrays."
This book is a review on the evolution of cell-based microarrays and an update to the author's earlier book Methods in Molecular Biology: Cell-Base...
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cena:
203,61 |
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Continuum Analysis of Biological Systems: Conserved Quantities, Fluxes and Forces
ISBN: 9783642544675 / Angielski / Twarda / 267 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book addresses the analysis, in the continuum regime, of biological systems at various scales, from the cellular level to the industrial one. It presents both fundamental conservation principles (mass, charge, momentum and energy) and relevant fluxes resulting from appropriate driving forces, which are important for the analysis, design and operation of biological systems. It includes the concept of charge conservation, an important principle for biological systems that is not explicitly covered in any other book of this kind. The book is organized in five parts: mass conservation;... This book addresses the analysis, in the continuum regime, of biological systems at various scales, from the cellular level to the industrial one. ... |
cena:
407,25 |
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Molecular Machines Involved in Peroxisome Biogenesis and Maintenance
ISBN: 9783709117873 / Angielski / Twarda / 543 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In eukaryotes, lipid metabolism requires the function of peroxisomes. These multitasking organelles are also part of species-specific pathways such as the glyoxylate cycle in yeast and plants or the synthesis of ether lipid in mammals. Proteins required for the biogenesis of peroxisomes typically assemble in large molecular complexes, which participate in membrane formation, protein transport, peroxisome duplication and - inheritance during cell division. Peroxisomal function is essential for life. Mutations in PEX genes, encoding for biogenesis factors, are often associated with lethal...
In eukaryotes, lipid metabolism requires the function of peroxisomes. These multitasking organelles are also part of species-specific pathways such as...
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cena:
610,90 |
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Cell Biology of the B Cell Receptor: Volume 123
ISBN: 9780128002667 / Angielski / Twarda / 168 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in...
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cena:
665,65 |
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Exchangers: Volume 73
ISBN: 9780128002230 / Angielski / Twarda / 438 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in understanding the current state and future prospects of a particular field. This volume on exchangers, in conjunction with a previous volume on cotransporters (volume 70), represents an up-to-date, systematic, and comprehensive review of all the major secondary active carrier proteins responsible for the absorption, secretion, and general transport of ions and solutes in mammalian organ... Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the ... |
cena:
615,97 |
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Advances in Applied Microbiology: Volume 88
ISBN: 9780128002605 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building... Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in micro... |
cena:
427,21 |
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Assembly of the Vasculature and Its Regulation
ISBN: 9781461266167 / Angielski / Miękka / 279 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progressively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis...
The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lin...
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cena:
407,25 |
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Folding of Disulfide Proteins
ISBN: 9781461429975 / Angielski / Miękka / 286 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book aims to cover the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, folding pathways, and folding mechanism of numerous extensively characterized disulfide proteins. Folding of Disulfide Proteins will be valuable supplementary reading for general biochemistry, biophysics, molecular biology, and cellular biology courses for graduate and undergraduate students. This book can also be used for specialized graduate-level biochemistry, biophysics, and molecular biology courses dedicated to protein folding as well as... This book aims to cover the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, foldin... |
cena:
447,98 |
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Cytochrome P-450: Structure, Mechanism, and Biochemistry
ISBN: 9781475799415 / Angielski / Miękka / 556 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Major advances have been made in recent years in clarifying the molecular properties of the cytochrome P-450 system. These advances stem, in practical terms, from the generally recognized importance of cytochrome P-450 in the metabolism of drugs and in the bioactivation of xenobiotics to toxic products. The fascinating multiplicity and differential regulation of cytochrome P-450 isozymes, and their ability to catalyze extraordinarily difficult chemical transformations, have independently drawn many chemists and biochemists into the P-450 circle. Progress in the field, from a technical point...
Major advances have been made in recent years in clarifying the molecular properties of the cytochrome P-450 system. These advances stem, in practical...
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cena:
814,55 |
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Innate Immunity and Inflammation
ISBN: 9781621820291 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The innate immune system is rapidly activated in response to infection and injury. It is a generic rather than pathogen-specific response that recruits immune cells, promotes inflammation, and mobilizes the adaptive immune system. Excessive or chronic inflammation may cause tissue damage, so a careful balance is required to restore homeostasis. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews the cellular and molecular mechanisms involved in innate immunity and all types of inflammation. The contributors examine the cell types...
The innate immune system is rapidly activated in response to infection and injury. It is a generic rather than pathogen-specific response that recruit...
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cena:
131,83 |
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Non Coding Rnas in Plants
ISBN: 9783642269998 / Angielski / Miękka / 510 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the most recent years, each of the RNA silencing pathways of plants have appeared to generate ncRNAs with dedicated functions, specialized biological activities and specific functional scopes. RNA silencing plays a crucial role in coordinating the expression, stability, protection and inheritance of eukaryotic genomes. It compromises several mechanisms, that invariably depend on core small non coding RNAs and that achieve dedicated sequence-specific functions. RNA silencing has been recognized to carry critical developmental, stress-response and bodyguard functions be coordinating the...
In the most recent years, each of the RNA silencing pathways of plants have appeared to generate ncRNAs with dedicated functions, specialized biologic...
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cena:
814,55 |
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Myocardial Preconditioning
ISBN: 9783662222089 / Angielski / Miękka / 285 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is about the unique ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myocardium - a phenomenon which is switched on by stress and termed myocardial preconditioning. This volume describes the main features and characteristics of preconditioning, with respect to the time-course of the protective effect of the phenomenon (first and second windows) and the different sequelae of myocardial ischaemia against which it protects, such as myocardial injury, arrhythmias and contractile dysfunction. The proposed mechanisms...
This book is about the unique ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myoc...
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cena:
541,33 |
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