Kategoria BISAC: Science >> Life Sciences - Biophysics

Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.

Ion channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts, the book is aimed at researchers in nanodevices and...

This book describes advances in implantable neural stimulation technology to restore partial sight to people who are blind from retinal degnerative diseases such as age-related macular degeneration and retintis pigmentosa. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The book summarizes the state of research and clinical practice in the field and reviews the current ideas and approaches of its leading researchers and practitioners.

This book provides a comprehensive yet accessible overview of all relevant topics in the field of radiation protection (health physics). The text is organized to introduce the reader to basic principles of radiation emission and propagation, to review current knowledge and historical aspects of the biological effects of radiation, and to cover important operational topics such as radiation shielding and dosimetry. The author's website contains materials for instructors including PowerPoint slides for lectures and worked-out solutions to end-of-chapter exercises. The book serves as an...

Cell motility is a fascinating example of cell behavior which is fundamentally important to a number of biological and pathological processes. It is based on a complex self-organized mechano-chemical machine consisting of cytoskeletal filaments and molecular motors. This network is highly dynamic, but able to show precise spatial and temporal organization. The machine is regulated by a complex network of biochemical reactions coupled to force and movement generating processes.

In general, the cytoskeleton is responsible for the movement of the entire cell and for movements within...

Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part I of this two-volume sequence, Biology, addresses the nanoscopic and microscopic scales. The nanoscale corresponds to the scale of biochemical reaction cascades involved in cell adaptation to mechanical stresses among other stimuli. The microscale is the scale of stress-induced tissue remodeling associated with acute or chronic loadings. The cardiovascular system, like any physiological...

Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part II of this two-volume sequence, Mechanics and Medical Aspects, refers to the extraction of input data at the macroscopic scale for modeling the cardiovascular system, and complements Part I, which focuses on nanoscopic and microscopic components and processes. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls...

This book is a lucid, straightforward introduction to the concepts and techniques of statistical physics that students of biology, biochemistry, and biophysics must know. It provides a sound basis for understanding random motions of molecules, subcellular particles, or cells, or of processes that depend on such motion or are markedly affected by it. Readers do not need to understand thermodynamics in order to acquire a knowledge of the physics involved in diffusion, sedimentation, electrophoresis, chromatography, and cell motility--subjects that become lively and immediate when the author...

This entertaining and informative book describes how living things bump up against non-biological reality. "My immodest aim," says the author, "is to change how you view your immediate surroundings." He asks us to wonder about the design of plants and animals around us: why a fish swims more rapidly than a duck can paddle, why healthy trees more commonly uproot than break, how a shark manages with such a flimsy skeleton, or how a mouse can easily survive a fall onto any surface from any height.

The book will not only fascinate the general reader but will also serve as an...

Based on a popular course given by the author at McGill University, the bookplaces the traditional...