Kategoria BISAC: Science >> Life Sciences - Biology

Molecular chaperones interact with virtually every newly synthesized protein. This volume assembles a collection of reviews on molecular chaperones that is both timely and basic. The book uniquely combines the basics of the subject area with the latest results. This makes it an excellent entrance for novices into the field and is suitable for teaching purposes. It also provides a source of substantial information for experts.

Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. This is the first book to highlight the medical implications, i.e. diseases, caused by alternative splicing. Alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences. The book also outlines possible targets for therapy.

Sphingolipids are fundamental to the structures of cell membranes, lipoproteins, and the stratum cornea of the skin. Many complex sphingolipids as well as simpler sphingoid bases and derivatives are highly bioactive as extra- and intracellular regulators of growth, differentiation, migration, survival, senescence, and numerous cellular responses to stress. This book provides many examples of exciting new developments in sphingolipid biology/sphingolipidology that are changing our understanding of how multicellular organisms grow, develop, function, age, and die. Key areas addressed include...

Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field of vascular biology in general requires in vitro and in vivo techniques in order to address the...

Recent advances in plant cell and molecular biology have opened new avenues for the improvement of crop plants in the genus "Brassica" - oilseeds and vegetables of worldwide economic importance. This volume reviews advances in various areas of "Brassica" biotechnology. It covers the use of rapid-cycle brassicas, tissue culture and gene transfer, molecular genetics, biotic and abiotic stress resistance, and molecular farming. Contributors are world-leading international "Brassica" researchers. The volume is an invaluable reference for plant breeders, researchers and graduate students in the...

Current state of knowledge and gaps in experimental evidence related to the physiologic role and toxicity of trace elements in human health were presented and discussed at an international joint conference in Hersonissos, Crete-Greece, in October 2007. The conference (ISTERH/NTES/HTES '07) constituted the VIIIth Conference of the International Society for Trace Element Research in Humans (ISTERH), the IXth Conference of the Nordic Trace Element Society (NTES), and the VIth Conference of the Hellenic Trace Element Society (HTES). The focus of the conference is put on the topics:

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This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug functions. This work is the first endeavor to present different aspects encompassing the above theme.

Research is fast paced and advances in RNA interference have recently opened up new opportunities for genetic experiments in human cell lines. However, the possibility to easily modify the genome still remains a powerful tool to investigate the function of coding and regulatory sequences in the vertebrate genome. DT40 has never been a quick and easy road to fame. It would be unfair to blame this on DT40 as it has proven to be a reliable and robust companion with fast doubling time, easy clonability and a relatively stable karyotype. If this model system is going to flourish over the next...

Gillott s thorough yet clear writing style continues to keep Entomology near the top of the class as a text for senior undergraduates, and for graduate students and professionals seeking an introduction to specific entomological topics. The author s long-held belief that an introductory entomology course should present a balanced treatment of the subject is reflected in the continued arrangement of the book in four sections: Evolution and Diversity, Anatomy and Physiology, Reproduction and Development, and Ecology. For the third edition, all chapters have been updated. This includes not...

This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although concentrating on the three vertebrate Myb family members, homologues from lower species are also discussed because of the light they are able to shed on the evolution and function of these proteins. Individual chapters describe the involvement of Myb proteins, in particular c-Myb, in normal and...