Kategoria BISAC: Nature >> Animals - Mammals

Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In Genotoxicity Assessment: Methods and Protocols, expert researchers in the field provide comprehensive genetic toxicology protocols. These include in vitro and in vivo protocols on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists...

Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity assays recommended by the "OECD guidelines for the testing of chemicals," this volume also covers other useful assays, such as some gene mutation assays, the comet assay in different species and applications, and the SMART assays of Drosophila. For all the assays, the book presents brief...

This book covers recent developments and possible pitfalls in the diagnosis of genetic movement disorders and related conditions. It is divided into three sections: technical and scientific aspects; clinical aspects with guidance towards work-up; and ethical and legal aspects of genetic testing in a clinical and research setting.

The first section includes chapters on genetic analysis and counselling with critical discussion of potential problems when interpreting the results. Clinical chapters summarize genetic forms of movement disorders including parkinsonism, tics and dystonia...

In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that were previously intractable with traditional genetic methods. Included in this latter category are common disorders that display multigenic inheritance, sporadic disorders, and very rare conditions...

Manatees, the gentle giants of Florida's lagoons and coastal habitats, can bring a smile to the face of anybody lucky enough to spy one. As manatees dip and roll through the water, crowds gather to watch them feed on aquatic vegetation. Whether they are congregating by the hundreds or resting or feeding alone, viewing these sea cows can provide anyone interested in nature with hours of tranquil pleasure.

Having survived for eons, today's manatees are now under constant threat due to our rapidly swelling human population. Their habitats are often devastated by development and...

Killer whales had always been seen as bloodthirsty sea monsters. That all changed when a young killer whale was captured off the west coast of North America and displayed to the public in 1964. Moby Doll -- as the whale became known -- was an instant celebrity, drawing 20,000 visitors on the one and only day he was exhibited. He died within a few months, but his famous gentleness sparked a worldwide...