Kategoria BISAC: Medical >> Toxicology

Although the fields of toxicology and human health assessment address similar problems, the experts from these fields do not meet very frequently. This text links ecotoxicology and classic human toxicology. It incorporates extensive reviews of exposure to toxicants, toxicokinetics and toxicodynamics, toxicology of mixtures, and risk assessment.

This book is the first major exploration of Indian political economy using a constructivist approach. Arguing that India's open-economy policy was made, justified, and continued on the basis of the idea of openness more than its tangible effect, the book explains what sustained the idea of openness, what philosophy, interpretations of history, and international context gave it support, justification, and persuasive force.

Drawing on a wide range of contemporary and historical sources, and going as far back as the 19^th century, the author reconstructs how Indian...

Despite the fact that the majority of research animals are rodents, the trainers at the Research Animal Resources Center at the University of Wisconsin-Madison found training material on the proper handling of mice and rats in biomedical research to be limited. So, they developed videos, narratives, pictures, and text to teach common handling, injection, and bleeding techniques.

The resulting DVDs and supporting manuals are complete training resources and refreshers for lab animal veterinarians, veterinary technicians, animal care staff, trainers, and researchers working with mice...

To date, a number of clinically important drugs have been identified that interact with commonly-used herbs and thus herb-drug interactions have become a safety concern in the use of herbal medicines. These drugs include (amongst others) warfarin, midazolam, digoxin, amitriptyline, indinavir, cyclosporine, tacrolimus and irinotecan. Importantly, many of these drugs have very narrow therapeutic indices. Most of them are substrates for cytochrome P450s (CYPs) and/or P-glycoprotein (P-gp). Because drug-herb interactions can significantly affect circulating levels of drug and, hence, alter the...

We are constantly exposed to a plethora of different chemicals, the majority of which are mostly uncharacterised with respect to their biological properties. This book provides an in depth overview on known neurotoxicity mechanisms for a group of industrial chemicals known as polybrominated diphenyl ethers (PBDEs).

This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book.

This book focuses on efficacy, toxicity, drug interactions, and abnormal clinical laboratory tests resulting from the use of herbal remedies. Although a few herbal remedies are safe and have efficacy (for example saw palmetto), many herbal remedies are toxic. This book guides in the interpretation of abnormal test results in otherwise healthy subjects due to use of herbal remedies. Chapters focus on interactions between herbals and pharmaceuticals, sources of contamination in herbal supplements, and analytical techniques used in the investigation of herbal remedies.

The twentieth century has seen a remarkable evolution of environmental health and environmental protection concerns and concepts in the United States. As a teacher of Environmental Health since the late 1950s, I have witnessed the many twists and turns that have marked the latter half of the century, and have had to seek continuously to explain these phenomena to my students in some rational manner. We have witnessed the following and more: great progress in controlling acute infectious diseases through successes in drinking water treatment and food processing; the emergence of greater...

In the continuing fight against organic environmental xenobiotics, the initial success attributed to bioremediation has paled, in part due to the low availability of xenobiotics entrapped within a soil or sediment matrix. This has generated a very significant wave of interest in the bioavailability issue. However, much experimental evidence is puzzling or contradictory, mechanistic theories are embryonic, and implications for the practice of bioremediation or concerning the natural fate of xenobiotics are still tentative.
The debate in Europe and the USA is vigorous. Eastern Europe,...

In 2000 OpdenKamp Registration & Notification organized a two-day symposium in The Hague, The Netherlands, on The Practical Applicability of Toxicokinetic Models in the Risk Assessment of Chemicals'. Several speakers from Europe and the United States were invited to present the different aspects. A vast range of areas was discussed in relation to toxicological modeling and risk assessment, such as occupational toxicology and biomonitoring, exposure to organic solvents and crop protection products, dose-response relations in carcinogenicity, regulatory toxicology, estimation of dermal...

Cadmium is currently one of the most important toxic metals in occupational and environmental toxicology. This book displays present knowledge on interactions between toxic metal cadmium and essential metals.

Building from the perspective of reproductive and developmental biology, Computational Methods for Reproductive and Developmental Toxicology provides a timely and comprehensive overview of approaches in reproductive and developmental toxicology.

The book, which is part of the QSAR in Environmental and Health Sciences series, is divided into three broad sections. The first provides a review of methods and approaches to meet the need for safety assessments in product development and regulatory approaches for environmental chemicals. The next one reviews the biological...

The herbai medicine industry is growing at an astounding rate. Trade group estimates suggest that total sales exceeded $4 billion dollars in 1999. Herbai remedies are for sale not just in health food stores, but in supermar kets, drug stores, and even discount warehouses. Along with the proliferation in sales has come a proliferation ofinformation sources. Not all ofthe sources are equally reliable, or even intelligible. Traditional herbalists c1assify thistle and mugwort as "cholagogues," substances used to make the gallbladder con tract and release bile. Medical school graduates are...

Immunotoxins represent a new class of human therapeutics that have widespread applications and a potential that has not yet been fully recognized since they were first conceived of by Paul Ehrlich in 1906. The majority of advances in the development and implementation of immunotoxins has occurred over the last 20 years. The reasons for this use of immunotoxins in basic science and clinical research are the powerful concurrent advances in genetic engineering and receptor physiology. Recombinant technology has allowed investigators to produce sufficient quantities of a homogeneous c- pound that...

Lead, mercury, arsenic, and cadmium are major toxic metals. All are environmental pollutants that can inflict harm on humans and other living creatures as well as adversely affect our air, water, soil, and food supply. They can poison not only us but also our progeny developing in the womb. They can break down the body's basic functions. This book describes the unique characteristics of each of the four major toxic metals, identifies the likely sources of our exposure, and offers in-depth, evidence based information, methods to test for its presence, and therapies to rid ti from our bodies.

Das Fachlexikon Toxikologie gibt den auf dem Gebiet des Umweltschutzes, der Arbeitshygiene und Toxikologie tatigen Wissenschaftlern und Praktikern ebenso ein Hilfsmittel in die Hand wie den mit dem Transport gefahrlicher Guter oder den mit der schadlosen Beseitigung toxischer Abprodukte Beschaftigten. Daneben wendet sich das Fachlexikon auch an die Mitarbeiter von Feuerwehr, Polizei, Rettungsdiensten, Zoll und anderen Kontrollbehorden sowie an Lehrende und Studierende naturwissenschaftlicher Disziplinen, die nach einem kompakten und zugleich kompetenten Ratgeber suchen.

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This book is the first significant contribution to thoroughly examine the potential hazards associated with snakes of the former family, Colubridae. This family contained >65% of living snake species (approximately 3,000 taxa) and has recently been split into multiple families. Many of these snakes produce oral secretions that contain toxins and other biologically-active substances. A large variety of these snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical...

Clarke's Analysis of Drugs and Poisons is the definitive source of analytical data for drugs and poisons. Written by over 40 international experts, the resource also boasts an editorial advisory board of over 45 world renowned scientists. This reference work has been completely revised and updated for the new edition, and comprises two volumes. * Volume one has been greatly expanded from 31 to 44 chapters providing extensive coverage of all methodology and analytical techniques. Of significant interest include: 1. Quality control and assessment - separated into two chapters to reflect the...

Environmental pollution is one of the main problems to confront humanity, with the heavy metals occupying a leading role among the most pernicious pollutants. The metals cause cancer and other sicknesses. Their cytotoxic, mutagenic and carcinogenic potentials are not fully understood, and any thorough investigation demands the combined efforts of scientists drawn from many different disciplines. But the effects of heavy metals are not all negative: some, like cis-DDP, and some ruthenium and tin complexes, have antitumour activity.
The idea underlying the present work is...

The Advanced Research Workshop in Bucharest from 20. to 22. 04. 1998 covered a broad spectrum of medical and pharmaceutical approaches dealing to maintenaning and restoring of the health of civilians and military personnel exposed to ionizing radiation or biological or chemical agents. The current capabilities and future perspectives for protection against NBC hazards were analyzed from an interdisciplinary perspective. In this context the planning of medical support operations was addressed as were aspects of practical medicine and forwardlooking scientific approaches. The main areas covered...