Kategoria BISAC: Medical >> Pain Management

This is the first part in a two-volume work on neuromodulation. It describes techniques and procedures applied in internal contact with non-neural tissues surrounding the nervous system (dura or cerebrospinal fluid), as in the case of epidural stimulation for pain or intrathecal drug application for the treatment of spasticity and pain. In addition, coverage also includes a special section on non-invasive functional neuroprosthetic systems.

Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially important drug targets in the treatment of pain. The roles of sodium channels in dental and visceral pain are also addressed. The emerging role of sodium channel Nav1.3 in neuropathic states is another important theme.

Authors from the pharmaceutical...

Vanilloids mediate their effects by selective agonism of an ion channel, the vanilloid receptor 1 (TRPV1). TRPV1 is a ligand-gated, non-selective, cation channel preferentially expressed in small-diameter, primary afferent neurons, including nociceptive sensory nerves. In addition to be activated by capsaicin and related vanilloids, TRPV1 responds to heat and extracellular acidification, and will integrate simultaneous exposures to these stimuli. The aim of this book is to summarize recent insights in the role of TRPV1 in pain and inflammation, and to discuss how modulation of this...

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Hammersley explores the uses and limitations of drug therapy for patients suffering from depression, anxiety and related disorders... Although many therapists welcome psychopharmacology for their clients, there are still many who feel that drug treatment is a stop-gap measure at best. This book provides an examination of the issue and offers some good advice about helping clients withdraw from drugs and cope with their...

Over the last two decades, Eastern psychology has provided fertile ground for therapists, as a cornerstone, a component, or an adjunct of their work. In particular, research studies are identifying the Buddhist practice of mindfulness--a non-judgmental self-observation that promotes personal awareness--as a basis for effective interventions for a variety of disorders.

The Clinical Handbook of Mindfulness is a clearly written, theory-to-practice guide to this powerful therapeutic approach (and related concepts in meditation, acceptance, and compassion) and its...