Foundations of Comparative Genomics
ISBN: 9780120887941 / Angielski / Twarda / 280 str. Termin realizacji zamówienia: ok. 2225 dni roboczych. This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several stateoftheart issues, such as...
This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Founda...


cena:
380,66 zł 
Biostatistics
ISBN: 9780195078107 / Angielski / Twarda / 368 str. Termin realizacji zamówienia: ok. 22 dni roboczych. This textbook takes a unique approach to explaining and demonstrating how to use and interpret statistics for the physiological, medical, and life sciences. The first third of the book presents an integrated overview and introduction to experimental design and statistical inference. The rest of the book provides an extensively crossreferenced set of 100 brief critiques of sample case studies embodying all the most common statistical errors or design problems found in the biological literature. These specific cases are effective for teaching the principles of biostatistics. The examples are...
This textbook takes a unique approach to explaining and demonstrating how to use and interpret statistics for the physiological, medical, and life sci...


cena:
1093,47 zł 
Statistics in Public Health : Quantitative Approaches to Public Health Problems
ISBN: 9780195114980 / Angielski / Miękka / 256 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Public health strives to improve the health of human populations, and prevent disease, disability, and death. Statisticsthe science of finding underlying patterns by analyzing variability and errors in collected datais essential to the understanding of disease patterns in human populations. Other quantitative methods, such as economics, decision theory, and mathematics, now constitute integral parts of the scientific basis for prioritysetting and evaluation in public health.
This book provides a broad conceptual treatment of the statistical issues underlying core public health... Public health strives to improve the health of human populations, and prevent disease, disability, and death. Statisticsthe science of finding under...


cena:
347,20 zł 
Modern Applied Biostatistical Methods : Using SPlus
ISBN: 9780195120257 / Angielski / Twarda / 480 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Statistical analysis typically involves applying theoretically generated techniques to the description and interpretation of collected data. In this text, theory, application and interpretation are combined to present the entire biostatistical process for a series of elementary and intermediate analytic methods. The theoretical basis for each method is discussed with a minimum of mathematics and is applied to a research data example using a computer system called SPLUS. This system produces concrete numerical results and increases one's understanding of the fundamental concepts and...
Statistical analysis typically involves applying theoretically generated techniques to the description and interpretation of collected data. In this t...


cena:
436,34 zł 
Dynamic Regression Models for Survival Data
ISBN: 9780387202747 / Angielski / Twarda / 470 str. Termin realizacji zamówienia: ok. 22 dni roboczych. In survival analysis there has long been a need for models that goes beyond the Cox model as the proportional hazards assumption often fails in practice. This book studies and applies modern flexible regression models for survival data with a special focus on extensions of the Cox model and alternative models with the specific aim of describing timevarying effects of explanatory variables. One model that receives special attention is Aalen's additive hazards model that is particularly well suited for dealing with timevarying effects. The book covers the use of residuals and resampling... In survival analysis there has long been a need for models that goes beyond the Cox model as the proportional hazards assumption often fails in pra... 

cena:
826,61 zł 
Statistical Genetics of Quantitative Traits : Linkage, Maps and QTL
ISBN: 9780387203348 / Angielski / Twarda / 365 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Most traits in nature and of importance to agriculture are quantitatively inherited. These traits are di?cult to study due to the complex nature of their inheritance. However, recent developments of genomic technologies provide a revolutionary means for unraveling the secrets of genetic variation in quantitative traits. Genomic te nologies allow the molecular characterization of polymorphic markers throughout the entire genome that are then used to identify and map the genes or quantitative trait loci (QTLs) underlying a quantitative trait based on linkage analysis. Statistical analysis is a...
Most traits in nature and of importance to agriculture are quantitatively inherited. These traits are di?cult to study due to the complex nature of th...


cena:
971,20 zł 
Statistical Reasoning in Medicine : The Intuitive PValue Primer
ISBN: 9780387329130 / Angielski / Miękka / 302 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Lowers the Learning Curve for Physicians and Researchers The successful Statistical Reasoning in Medicine: The Intuitive Pvalue Primer, with its novel emphasis on patient and community protection, illustrated the correct use of statistics in health care research for healthcare workers. Through clear explanations and examples, this book provided the nonmathematician with a foundation for understanding the underlying statistical reasoning process in clinical research, the core principles of research design, and the correct use of statistical inference and pvalues. The... Lowers the Learning Curve for Physicians and Researchers The successful Statistical Reasoning in Medicine: The Intuitive Pvalue Primer, wi... 

cena:
441,05 zł 
Statistical Methods in Bioinformatics : An Introduction
ISBN: 9780387400822 / Angielski / Twarda / 598 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community. This book provides an introduction to some of these new methods. The main biological topics treated include sequence... Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated t... 

cena:
537,44 zł 
Analysis of Quantal Response Data
ISBN: 9780412317507 / Angielski / Twarda / 512 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Quantal response (sometimes called dosereponse) data arise in many areas, both through experimental and observational studies. Particular emphasis is placed in this book on applications in bioassay and toxicology. For instance, data for analysis may arise from routine clinical trials, or from studies of safe doses of drugs. Throughout the material is motivated by a wide range of practical examples.
Quantal response (sometimes called dosereponse) data arise in many areas, both through experimental and observational studies. Particular emphasis is...


cena:
592,87 zł 
Statistical Methods in Spatial Epidemiology
ISBN: 9780470014844 / Angielski / Twarda / 398 str. Termin realizacji zamówienia: ok. 2530 dni roboczych. Spatial epidemiology is the description and analysis of the geographical distribution of disease. It is more important now than ever, with modern threats such as bioterrorism making such analysis even more complex. This second edition of Statistical Methods in Spatial Epidemiology is updated and expanded to offer a complete coverage of the analysis and application of spatial statistical methods. The book is divided into two main sections: Part 1 introduces basic definitions and terminology, along with map construction and some basic models. This is expanded upon in Part II by applying...
Spatial epidemiology is the description and analysis of the geographical distribution of disease. It is more important now than ever, with modern thre...


cena:
591,99 zł 
Applied Mixed Models in Medicine
ISBN: 9780470023563 / Angielski / Twarda / 478 str. Termin realizacji zamówienia: ok. 2530 dni roboczych. A mixed model allows the incorporation of both fixed and random variables within a statistical analysis. This enables efficient inferences and more information to be gained from the data. The application of mixed models is an increasingly popular way of analysing medical data, particularly in the pharmaceutical industry. There have been many recent advances in mixed modelling, particularly regarding the software and applications. This new edition of a groundbreaking text discusses the latest developments, from updated SAS techniques to the increasingly wide range of applications. Presents an...
A mixed model allows the incorporation of both fixed and random variables within a statistical analysis. This enables efficient inferences and more in...


cena:
554,00 zł 
Disease Surveillance : A Public Health Informatics Approach
ISBN: 9780470068120 / Angielski / Twarda / 488 str. Termin realizacji zamówienia: ok. 2225 dni roboczych. An uptodate and comprehensive treatment of biosurveillance techniques
With the worldwide awareness of bioterrorism and drugresistant infectious diseases, the need for surveillance systems to accurately detect emerging epidemicsis essential for maintaining global safety. Responding to these issues, Disease Surveillance brings together fifteen eminent researchers in the fields of medicine, epidemiology, biostatistics, and medical informatics to define the necessary elements of an effective disease surveillance program, including research, development, implementation, and operations. The... An uptodate and comprehensive treatment of biosurveillance techniques
With the worldwide awareness of bioterrorism and drugresistant infectious ... 

cena:
644,33 zł 
Genetic Epidemiology : Fundamental Concepts
ISBN: 9780470853269 / Angielski Termin realizacji zamówienia: ok. 2530 dni roboczych. Genetic epidemiology is a rapidly developing field, and has continued to grow enormously in international importance over the last ten years. This book provides a unified text that draws together material genetics, epidemiology, public health and statistics. Developed from the authors extensive experience of teaching undergraduate and graduate level courses in genetic epidemiology and statistical genetics, it contains numerous examples drawn from the literature and the authors' personal experience, and features exercises with worked answers.
Features include: A truly introductory level... Genetic epidemiology is a rapidly developing field, and has continued to grow enormously in international importance over the last ten years. This boo...


cena:
225,89 zł 
Statistical Methods for DoseFinding Experiments
ISBN: 9780470861233 / Angielski / Twarda / 336 str. Termin realizacji zamówienia: ok. 2530 dni roboczych. Dosefinding experiments define the safe dosage of a drug in development, in terms of the quantity given to a patient. Statistical methods play a crucial role in identifying optimal dosage. Used appropriately, these methods provide reliable results and reduce trial duration and costs. In practice, however, dosefinding is often done poorly, with widely used conventional methods frequently being unreliable, leading to inaccurate results. However, there have been many advances in recent years, with new statistical techniques being developed and it is important that these new techniques are...
Dosefinding experiments define the safe dosage of a drug in development, in terms of the quantity given to a patient. Statistical methods play a cruc...


cena:
486,47 zł 
Competing Risks : A Practical Perspective
ISBN: 9780470870686 / Angielski / Twarda / 242 str. Termin realizacji zamówienia: ok. 2530 dni roboczych. The need to understand, interpret and analyse competing risk data is key to many areas of science, particularly medical research. There is a real need for a book that presents an overview of methodology used in the interpretation and analysis of competing risks, with a focus on practical applications to medical problems, and incorporating modern techniques. This book fills that need by presenting the most uptodate methodology, in a way that can be readily understood, and applied, by the practitioner.
The need to understand, interpret and analyse competing risk data is key to many areas of science, particularly medical research. There is a real need...


cena:
431,59 zł 
Biostatistics : A Methodology For the Health Sciences
ISBN: 9780471031857 / Angielski / Twarda / 896 str. Termin realizacji zamówienia: ok. 2225 dni roboczych. A respected introduction to biostatistics, thoroughly updated and revised
The first edition of Biostatistics: A Methodology for the Health Sciences has served professionals and students alike as a leading resource for learning how to apply statistical methods to the biomedical sciences. This substantially revised Second Edition brings the book into the twentyfirst century for today's aspiring and practicing medical scientist. This versatile reference provides a wideranging look at basic and advanced biostatistical concepts and methods in a format calibrated to individual interests and... A respected introduction to biostatistics, thoroughly updated and revised
The first edition of Biostatistics: A Methodology for the Health Sciences ... 

cena:
806,42 zł 
Randomization in Clinical Trials: Theory and Practice
ISBN: 9780471236269 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 22 dni roboczych. A unique overview that melds the concepts of conditional probability and stochastic processes into reallife applications
The role of randomization techniques in clinical trials has become increasingly important. This comprehensive guide combines both the applied aspects of randomization in clinical trials with a probabilistic treatment of properties of randomization. Taking an unabashedly nonBayesian and nonparametric approach to inference, the book focuses on the linear rank test under a randomization model, with added discussion on likelihoodbased inference as it relates to... A unique overview that melds the concepts of conditional probability and stochastic processes into reallife applications
The role of ran... 

cena:
828,39 zł 
Design and Analysis of Clinical Experiments
ISBN: 9780471349914 / Angielski / Miękka / 448 str. Termin realizacji zamówienia: ok. 2225 dni roboczych. First published in 1986, this unique reference to clinical experimentation remains just as relevant today. Focusing on the principles of design and analysis of studies on human subjects, this book utilizes and integrates both modern and classical designs. Coverage is limited to experimental comparisons of treatments, or in other words, clinical studies in which treatments are assigned to subjects at random.
First published in 1986, this unique reference to clinical experimentation remains just as relevant today. Focusing on the principles of design and an...


cena:
669,66 zł 
Applied Spatial Statistics for Public Health Data
ISBN: 9780471387718 / Angielski / Twarda / 520 str. Termin realizacji zamówienia: ok. 1620 dni roboczych. While mapped data provide a common ground for discussions between the public, the media, regulatory agencies, and public health researchers, the analysis of spatially referenced data has experienced a phenomenal growth over the last two decades, thanks in part to the development of geographical information systems (GISs). This is the first thorough overview to integrate spatial statistics with data management and the display capabilities of GIS. It describes methods for assessing the likelihood of observed patterns and quantifying the link between exposures and outcomes in spatially...
While mapped data provide a common ground for discussions between the public, the media, regulatory agencies, and public health researchers, the analy...


cena:
949,98 zł 
Statistical Methods for the Analysis of Biomedical Data
ISBN: 9780471394051 / Angielski / Twarda / 712 str. Termin realizacji zamówienia: ok. 2225 dni roboczych. The new edition adds a chapter on multiple linear regression in biomedical research, with sections including the multiple linear regressions model and least squares; the ANOVA table, parameter estimates, and confidence intervals; partial ftests; polynomial regression; and analysis of covariance.
* Organized by problem rather than method, so it guides readers to the correct technique for solving the problem at hand. The new edition adds a chapter on multiple linear regression in biomedical research, with sections including the multiple linear regressions model and...


cena:
806,42 zł 