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Phosphoinositide 3-Kinase in Health and Disease: Volume 1
ISBN: 9783642265228 / Angielski / Miękka / 310 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here
From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been ca...
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805,10 |
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FC T2 Układ krążenia - Konturek Stanisław
ISBN: 9788323314813 / Polski / Miękka / 297 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. „Nie upraszczając części czysto teoretycznej, tzn. mechanizmów skurczu mięśnia sercowego, czynności bodźcotwórczej układu przewodzącego, podstaw elektro- i fono-kardiografii, Autor często nawiązuje do kliniki, wzbogacając w ten sposób podręcznik fizjologii o patofizjologię chorób układu sercowo-naczyniowego, w tym zwłaszcza o miażdżycę naczyń, nadciśnienie i zawały mięśnia sercowego. Omawia metody badań, z którymi »na co dzień« ma do czynienia kardiolog i klinicysta. Student po raz pierwszy spotyka się tu z problemami angioplastyki lub zabiegów...
„Nie upraszczając części czysto teoretycznej, tzn. mechanizmów skurczu mięśnia sercowego, czynności bodźcotwórczej układu przewodzącego, ...
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50,00 |
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Airway Epithelium
ISBN: 9781615043743 / Angielski / Miękka / 148 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The airways are lined with a film of fluid 10 ?m deep that acts as the first line of defense against inhaled pathogens, dirt, and noxious vapors. In this title, after reviewing the basic structure of mammalian airway epithelium, the author discusses its various defensive functions and how they are altered in airway disease.
The airways are lined with a film of fluid 10 ?m deep that acts as the first line of defense against inhaled pathogens, dirt, and noxious vapors. In t...
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218,49 |
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Circadian Clocks
ISBN: 9783642259494 / Angielski / Twarda / 417 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is placed on the importance of circadian clocks for the timing of therapeutic interventions.
This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clo...
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1610,24 |
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Omega-3 Fatty Acids and Health
ISBN: 9781461358602 / Angielski / Miękka / 359 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The evidence that omega-3 fatty acids are essential for human development and most helpful to achieve good health throughout life is clearly documented by Dr. Joyce Nettleton in her new book Omega-3 Fatty Acids and Health. Omega 3 fatty acids are produced by the plants of the land and sea. The tissues of the body require the omega-3 fatty acids for their proper functioning just as they also need the omega-6 essential fatty acids. It is probable in man's evolutionary development that there has always been the proper balance between these two groups of essential fatty acids, but in the modern...
The evidence that omega-3 fatty acids are essential for human development and most helpful to achieve good health throughout life is clearly documente...
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402,53 |
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Genetic Influences on Human Fertility and Sexuality: Theoretical and Empirical Contributions from the Biological and Behavioral Sciences
ISBN: 9781461370123 / Angielski / Miękka / 331 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences on fertility, sexuality, and related processes. Genetic Influences on Human Fertility and Sexuality takes the next step, and presents a number of successful empirical searches for such genetic influence on a broad range of processes, such as puberty, marriage, sexual behavior, and twinning. Employing a broad range of methodological approaches, including molecular and behavioral genetics, this book weaves a new theoretical framework...
Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences...
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cena:
805,10 |
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Autophagy and Cancer
ISBN: 9781461465607 / Angielski / Twarda / 261 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a...
With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about auto...
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cena:
603,81 |
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Man Is the Extension of Woman: Know the Ultimate Truth about Yourself
ISBN: 9781475949445 / Angielski / Miękka / 102 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. If a woman lives longer than her lifetime, will she be converted into a man? A surgeon thinks so and tries to prove this in very lucid and step by step manner. In fact he goes ahead and states that if man lives long enough, he too will be converted into woman and they don't have to undergo any operation or take any medication to achieve this. As one reads this book, one will feel invisible shadow of this truth looming over one's entire life.
If a woman lives longer than her lifetime, will she be converted into a man? A surgeon thinks so and tries to prove this in very lucid and step ... |
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49,91 |
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Phosphoinositide 3-Kinase in Health and Disease: Volume 2
ISBN: 9783642265303 / Angielski / Miękka / 306 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many. However, targeted therapies almost invariably encounter roadblocks, often exposing unresolved questions in the basic understanding of the target
PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impa...
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cena:
805,10 |
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Human Gametes and Preimplantation Embryos: Assessment and Diagnosis
ISBN: 9781461466505 / Angielski / Twarda / 306 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by... In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. Howeve... |
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603,81 |
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Satiation, Satiety and the Control of Food Intake: Theory and Practice
ISBN: 9780857095435 / Angielski / Twarda / 432 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With growing concerns about the rising incidence of obesity, there is interest in understanding how the human appetite contributes to energy balance and how it might be affected by the foods we consume, as well as other cultural and environmental factors. Satiation, satiety and the control of food intake provides a concise and authoritative overview of these areas. Part one introduces the concepts of satiation and satiety and discusses how these concepts can be quantified. Chapters in part two focus on biological factors of satiation and satiety before part three moves on to explore food...
With growing concerns about the rising incidence of obesity, there is interest in understanding how the human appetite contributes to energy balance a...
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847,31 |
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Techniques in Animal Cytogenetics
ISBN: 9783642640957 / Angielski / Miękka / 230 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A better "casting" could not be conceived. The authors of this book are gold smiths on the subject. I have followed their work since their "entry" into cyto genetics and I have a high esteem for them. I consider it an honour to be asked to write the preface of their opus. Paul Popescu, Directeur de Recherche at INRA, has also played a promi nent part in the development of animal cytogenetics, especially in domestic animals. He is able to tell you the cost of a translocation in a pig breeding farm or a cow population: a fortune P. Popescu has played a great part in gene mapping of these...
A better "casting" could not be conceived. The authors of this book are gold smiths on the subject. I have followed their work since their "entry" int...
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cena:
201,24 |
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Microbial Growth on C1 Compounds: Proceedings of the 8th International Symposium on Microbial Growth on C1 Compounds, Held in San Diego, U.S.A., 27 Au
ISBN: 9789401065801 / Angielski / Miękka / 363 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 8th International Symposium on Microbial Growth on C1 Compounds was held at the Bahia Resort Hotel, San Diego, CA, 27 August-1 September, 1995. A total of 160 participants from 18 countries were registered. Eight Scientific Sessions were held in which 45 papers were presented, and 114 posters were displayed and discussed in 3 separate poster sessions.
The Symposium covered a broad range of topics, including acetogenesis, methanogenesis, CO2 fixation, lithoautotrophy, carboxidotrophy, methylotrophy and methanotrophy. The theme of the Symposium was mechanistic,... The 8th International Symposium on Microbial Growth on C1 Compounds was held at the Bahia Resort Hotel, San Diego, CA, 27 August-1 Septembe...
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402,53 |
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Comparative Medicine: Anatomy and Physiology
ISBN: 9783709115589 / Angielski / Twarda / 300 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This new volume provides a concise overview of the most basic and exciting chapters of comparative medicine with regards to physiology and function in healthy individuals. The book includes core concepts in anatomy and physiology in human and animal models, which are key to understanding comparative medicine and to making contributions to research in this area. While writing this book, the authors were in constant interdisciplinary dialogue. They aim to contribute to improvements in quality of life for human and animal patients. This new volume provides a concise overview of the most basic and exciting chapters of comparative medicine with regards to physiology and function... |
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603,81 |
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Between the Regular and the Particular in Speech and Language
ISBN: 9783631586860 / Angielski / Twarda / 264 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume ranges widely even wildly over many speech and language disciplines and typologically diverse languages, demonstrating that the search for regularities traditionally at the forefront of linguistic work cannot afford to ignore close analysis of very particular, even idiosyncratic areas of language behaviour. This is illustrated especially in the relationship between phonetic detail and speaker characteristics, on the one hand, and between phonetic detail and phonological structure, on the other, while also including phonological analysis relevant to sound change and markedness...
This volume ranges widely even wildly over many speech and language disciplines and typologically diverse languages, demonstrating that the search for...
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428,62 |
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Oxford Handbook of Event-Related Potential Components
ISBN: 9780199328048 / Angielski / Miękka / 664 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Event-related potentials (ERPs) have been used for decades to study perception, cognition, emotion, neurological and psychiatric disorders, and lifespan development. ERPs consist of multiple components and reflect a specific neurocognitive process. In the past, there was no single source that could be consulted to learn about all the major ERP components; learning about a single ERP component required reading dozens or even hundreds of separate journal articles and book chapters. The Oxford Handbook of Event-Related Potential Components fills this longstanding void with a...
Event-related potentials (ERPs) have been used for decades to study perception, cognition, emotion, neurological and psychiatric disorders, and lifesp...
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783,49 |
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The Cochlea
ISBN: 9781461268918 / Angielski / Miękka / 551 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Knowledge about the structure and function of the inner ear is vital to an understanding of vertebrate hearing. This volume presents a detailed overview of the mammalian cochlea from its anatomy and physiology to its biophysics and biochemistry. The nine review chapters, written by internationally distinguished auditory researchers, provide a detailed and unified introduction to sound processing in the cochlea and the steps by which the ensuing signals are prepared for the central nervous system.
Knowledge about the structure and function of the inner ear is vital to an understanding of vertebrate hearing. This volume presents a detailed overvi...
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cena:
885,61 |
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Developmental Biology of Flowering Plants
ISBN: 9781461270546 / Angielski / Miękka / 354 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The study of the development of flowering plants may be said to be in the throes of a revolution. The literature on the subject is extensive and continues to grow rapidly as new discoveries pile one on top of the other; moreover, these striking advances in our knowledge have put plant developmental biology well ahead of other aspects of the study of plants. This has come about after a period of neglect and stagnation in the field and has been triggered by the power of recombinant DNA technology to analyze genetic information and by a fruitful cross-fertilization between physiology, genetics,...
The study of the development of flowering plants may be said to be in the throes of a revolution. The literature on the subject is extensive and conti...
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cena:
201,24 |
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Analysis and Assessment of Cardiovascular Function
ISBN: 9781461272618 / Angielski / Miękka / 387 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The objective of this book is to provide the researcher and clinician with the recent developments in the analysis and assessment of cardiovascular func- tion. The chapters are organized into sections that correspond with the various anatomical levels of the cardiovascular system. To a large extent, recent focus on the cardiovascular system function has been directed at the molecular level to the near exclusion of the tissue and organ function. While this may be useful in developing new therapeutic drugs, it does not aid the cardiologist or surgeon, who routinely deal with patient symptoms....
The objective of this book is to provide the researcher and clinician with the recent developments in the analysis and assessment of cardiovascular fu...
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cena:
402,53 |
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Histophysiology of the Immune System: The Life History, Organization, and Interactions of Its Cell Populations
ISBN: 9781468455373 / Angielski / Miękka / 926 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 9th International Conference on Lymphatic Tissues and Germinal Centres in Immune Reactions was held in Oslo, 9-14 August, 1987. These conferen- ces, by the regular devotees just referred to as the germinal centre con- ferences or GCC, have been held regularly at roughly three-year intervals since 1966. The credo of these conferences is "in vivo veritas," signifying that investigating components, like molecules and cells, only gives partial truth. The components must ultimately be explored in their natural con- text, to see how they interact with other parts and are integrated to a whole....
The 9th International Conference on Lymphatic Tissues and Germinal Centres in Immune Reactions was held in Oslo, 9-14 August, 1987. These conferen- ce...
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cena:
402,53 |
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