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Orphan G Protein-Coupled Receptors and Novel Neuropeptides
ISBN: 9783642097058 / Angielski / Miękka / 259 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The chapters of this book review the latest research in the field. Most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is placed not only on their discovery but also on their functional significance.
The chapters of this book review the latest research in the field. Most of them are written by the original discoverers of the respective novel neurop...
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806,99 |
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Plant Cell Biotechnology
ISBN: 9783642081651 / Angielski / Miękka / 353 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the past there were many attempts to change natural foodstuffs into high-value products. Cheese, bread, wine, and beer were pro duced, traditionally using microorganisms as biological tools. Later, people influenced the natural process of evolution by artificial selection. In the 19th century, observations regarding the depen dence of growth and reproduction on the nutrient supply led to the establishment of agricultural chemistry. Simultaneously, efforts were directed at defining the correlation between special forms of morphological differentiation and related biochemical processes. New...
In the past there were many attempts to change natural foodstuffs into high-value products. Cheese, bread, wine, and beer were pro duced, traditionall...
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806,99 |
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The Tumor Microenvironment
ISBN: 9781441966148 / Angielski / Twarda / 770 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of the tumor. Early on, the elements of what we now call the tumor microenvironment...
The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial ce...
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806,99 |
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Chiral Recognition in Separation Methods: Mechanisms and Applications
ISBN: 9783642124440 / Angielski / Twarda / 352 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December 2005, the journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a particular eld or topic. The "A-page" section was prepared for a broad audience of chemists including industrial professionals, s- dents as well as academics looking for information outside their eld of expertise. 1 Daniel W. Armstrong, one...
What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December 2005, the journa...
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806,99 |
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Drug Product Development for the Back of the Eye
ISBN: 9781441999191 / Angielski / Twarda / 592 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs.
Specific topics covered in this book include:
This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including s... |
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806,99 |
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Cancer Associated Viruses
ISBN: 9781441999993 / Angielski / Twarda / 866 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This...
The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to th...
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806,99 |
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Molecular Targeting in Oncology
ISBN: 9781617376535 / Angielski / Miękka / 728 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer and is structured in a way so readers may begin with chapters that most interest them and work through the rest of the chapters in the order of their choice. The volume is divided into five sections that cover the most important elements of drug development. The first section focuses... In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphas... |
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806,99 |
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Molluscs: From Chemo-Ecological Study to Biotechnological Application
ISBN: 9783642068102 / Angielski / Miękka / 387 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This is the first book on molluscs as sources for pharmaceutical drugs. Marine molluscs are very promising candidates for a wide range of biotechnological applications. For example, they possess analgesic drugs more potent than morphine and very effective anticancer agents. International experts provide coverage of the most stimulating topics related to molluscs. This knowledge of their history and current studies opens the door to the future. This is the first book on molluscs as sources for pharmaceutical drugs. Marine molluscs are very promising candidates for a wide range of biotechno... |
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806,99 |
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Heterocyclic Antitumor Antibiotics
ISBN: 9783642068140 / Angielski / Miękka / 252 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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806,99 |
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DNA Topoisomerases and Cancer
ISBN: 9781461403227 / Angielski / Twarda / 443 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various... DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for t... |
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806,99 |
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Antidepressants: New Pharmacological Strategies
ISBN: 9781617370489 / Angielski / Miękka / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book, leading-edge investigators offer effective strategies to improve current antidepressive therapies and suggest molecular, biological, and genetic approaches that will lead to the development of novel antidepressants. The contributors' critical reviews and commentaries illuminate our understanding of the mechanism(s) responsible for antidepressant action. The book's goal is to move beyond current biogenic amine-based concepts and therapies to the development of new and improved antidepressants that are more effective and have a more rapid onset than current.
In this book, leading-edge investigators offer effective strategies to improve current antidepressive therapies and suggest molecular, biological, and...
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806,99 |
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Multiple Drug Resistance in Cancer 2: Molecular, Cellular and Clinical Aspects
ISBN: 9789048151080 / Angielski / Miękka / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Resistance to chemotherapy, and especially multi-drug resistance, represents a significant barrier to the successful treatment of cancer. This multi-author volume brings together a wide range of up-to-date reviews on different aspects of our knowledge of drug-resistance mechanisms, written by experts in the different areas. Particular attention is paid to recently discovered mechanisms relating to oncogene expression and in particular to proteins involved in regulation and execution of apoptosis. Other important topics covered include DNA repair, topoisomerases, cell cycle control, ...
Resistance to chemotherapy, and especially multi-drug resistance, represents a significant barrier to the successful treatment of cancer. This multi...
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Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes
ISBN: 9789048177363 / Angielski / Miękka / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks. Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances. In addition, the funtionalization of nanotubes has not... Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemic... |
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Anticancer Drug Resistance: Advances in Molecular and Clinical Research
ISBN: 9780792328360 / Angielski / Twarda / 294 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomenon of drug resistance is largely responsible for these failures and continues to be an area of active investigation.
Since the last volume in this series, we have learned that the energy-dependent drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of... Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, te...
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806,99 |
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Stem Cells and Cancer
ISBN: 9781617379208 / Angielski / Miękka / 346 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This first edition of Stem Cells and Cancer gives a current perspective on the role of stem cells in cancer and strategies for novel therapies directed toward tumor stem cells. It represents a compendium of cutting edge research by experts in the field.
This first edition of Stem Cells and Cancer gives a current perspective on the role of stem cells in cancer and strategies for novel therapies directe...
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806,99 |
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Transporters as Targets for Drugs
ISBN: 9783642099694 / Angielski / Miękka / 254 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Transporters are proteins that span the plasma membrane and regulate the traf?c of small molecules in and out of the cell. They play a particularly important role in chemical signalling between neurons in the CNS, where they act to control the concentration of neurotransmitters in the synapse. In most systems the termination of chemical transmission is achieved by rapid uptake of the transmitter molecule from the synapse by transporters located on the synaptic terminal or surrounding glial cells. Another key role for transporters is in excluding undesirable xenobiotics from the cell, whilst...
Transporters are proteins that span the plasma membrane and regulate the traf?c of small molecules in and out of the cell. They play a particularly im...
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806,99 |
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Design and Analysis of Vaccine Studies
ISBN: 9781461424888 / Angielski / Miękka / 390 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Immunizationisoneofthegreatadvancesinpublichealth. Figure0. 1showsacamel with a solar-powered refrigerator on his back carrying vaccines across a hot desert to the far reaches of civilization. Many vaccines contain live viruses that need to be kept cold, or the vaccine viruses will die, and the vaccines will lose their ability to produce an immune response. Thus a continuous chain of refrigeration, the cold chain, from the origin to delivery of some vaccines needs to be maintained. The inspiration of the camel image is that it represents the dedication of the world to bring vaccines to...
Immunizationisoneofthegreatadvancesinpublichealth. Figure0. 1showsacamel with a solar-powered refrigerator on his back carrying vaccines across a hot ...
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806,99 |
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Experimental and Clinical Metastasis: A Comprehensive Review
ISBN: 9781461436843 / Angielski / Twarda / 472 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metastatic disease is the most lethal aspect of human malignancies, making the understanding and continued research of the process of metastasis a crucial step in treating cancer. The proposed book, entitled "Experimental and Clinical Metastasis: A Comprehensive Review" aims to provide a clear and extensive review of the clinical and experimental implications of metastatic disease. This work focuses on recent contributions to the field of metastasis, and will highlight crucial findings in the molecular understanding of disseminated disease as well as standard and personalized medicine...
Metastatic disease is the most lethal aspect of human malignancies, making the understanding and continued research of the process of metastasis a cru...
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806,99 |
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Molecular, Clinical and Environmental Toxicology: Volume 3: Environmental Toxicology
ISBN: 9783764383398 / Angielski / Twarda / 574 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially...
Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and...
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806,99 |
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Behavioral Neurobiology of Anxiety and Its Treatment
ISBN: 9783642263750 / Angielski / Miękka / 350 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The book is part of a series on Current Topics in Behavioral Neurosciences, which has as its focus anxiety and its treatment. We have brought together a distinguished cadre of authors with the aim of covering a broad array of topics related to anxiety disorders, ranging from clinical diagnosis, epidemiology, preclinical neuroscience, and animal models to established and innovative therapeutic approaches. The book aims at bridging these disciplines to provide an update of literature relevant to understanding anxiety, its consequences, and its management. Following is a brief overview of the...
The book is part of a series on Current Topics in Behavioral Neurosciences, which has as its focus anxiety and its treatment. We have brought together...
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cena:
806,99 |
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