Kategoria BISAC: Medical >> Pharmacology

Safety aspects have become an outstanding issue in the process of drug discovery and development. Until 15 years ago, drug discovery and evaluation was a sequential process starting with the selection of the most active compound from a series of newly synthesized compounds by means of special pharmacological assays. Safety aspects were addressed by pharmacological testing of the selected compound in high doses in tests directed at indications other than the intended indication of the new compound. These tests were followed by pharmacokinetic studies, which were mainly aimed at confirming...

Psychopharmacology is the study of the effects of psychoactive drugs on the functioning of the central nervous system at all levels of analysis, thus embracing cognition, behavior, psychological states, neurophysiology, neurochemistry, gene expression, and molecular biology. It includes, as an integral part of its domain, the interaction of environmental and genetic factors with psychoactive drug action, the medicinal and social uses of drugs, and the misuse and abuse of psychoactive substances.

The aim of this comprehensive encyclopedia is to provide detailed information on...

Widely distributed throughout plant families, flavonoids give many flowers and fruits their vibrant colors. They also play a role in protecting the plants from microbe and insect attacks. More importantly, the consumption of foods containing flavonoids has been linked to numerous health benefits. Recent research indicates that flavonoids can be nutritionally helpful by triggering enzymes that reduce the risk of certain cancers, heart disease, and age-related degenerative diseases. Foods that contain high amounts of flavonoids include blueberries, red beans, cranberries, and blackberries....

From the Foreword

Umberto Quattrocchi has brought us some amazing and useful works through the various dictionaries that he has compiled. This time it is for two very important plant families the palms and the cycads that are synthesized here in these two volumes. Each entry is fascinating not just for the botany and full nomenclature of the plant species but for all the associated uses, folklore and interactions with other organisms. ...These entries are fascinating glimpses of natural history. ... Botanists, conservationists, ethnobotanists, anthropologists, geographers, bird...

Bacterial and parasitic diseases are the second leading cause of death worldwide, according to a report by the London School of Economics. Due to the emergence of drug-resistant "superbugs," like methicillin-resistant Staphylococcus aureus (MRSA), traditional antibiotics such as penicillin and its derivatives are in danger of becoming obsolete. In an effort to combat this problem, pharmaceutical companies continue to research new and effective antibiotics.
The Dictionary of Antibiotics and Related Substances with CD-ROM, Second Edition is a definitive reference work...

If you're working on or studying the effects of drug metabolisms, then this reference is for you

Handbook of Metabolic Pathways of Xenobiotics is an essential new reference which presents the metabolic fate of xenobiotics in animals and plants, and shows the metabolic pathways in the environment.

Presenting a comprehensive guide to understanding the metabolisms of xenobiotics, the Handbook of Metabolic Pathways of Xenobiotics spans five volumes: Volumes 1-2 are Review Articles and Volumes 3-5 are Compound Articles. Review Articles present detailed...