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Molecular Endocrinology of Cancer
ISBN: 9780521159494 / Angielski / Miękka / 442 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. One third of human cancers have a hormonal basis. Breast cancer, the most common cancer of women, is increasing in many countries, as is prostate cancer, the second most common cancer of men. Concurrently, molecular biology has refined the definition of hormones to include the interaction between tumor cells and both locally and distantly secreted factors. This volume in the series Cancer: Clinical Science in Practice considers aspects of hormonal cancer, including the molecular basis for the autocrine and paracrine regulation of cancer, molecular strategies for cancer detection, strategies...
One third of human cancers have a hormonal basis. Breast cancer, the most common cancer of women, is increasing in many countries, as is prostate canc...
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302,61 zł |
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Early Brain Injury or Cerebral Vasospasm, Volume 1: Pathophysiology
ISBN: 9783709103524 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. More than 40 articles provide an extensive coverage of clinical and basic science advances over the last three years of research on subarachnoid hemorrhage-induced brain injuries. Early brain injury, the new frontier of subarachnoid hemorrhage research, which may be a key contributor to the high mortality and morbidity, promotes collaborative efforts from neurosurgery, neurology, neuro-ICU into other interrelated fields and basic neurosciences. For the first time, subarachnoid hemorrhage research is almost equally divided by early brain injury and cerebral vasospasm, mechanistic...
More than 40 articles provide an extensive coverage of clinical and basic science advances over the last three years of research on subarachnoid hemor...
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806,99 zł |
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Reviews of Physiology, Biochemistry and Pharmacology
ISBN: 9783540002284 / Angielski / Twarda / 218 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Protein transport events occurring at the endoplasmic reticulum (ER) of eukaryotic cells and the cytoplasmic membrane of prokaryotic organisms share many similarities. Resident proteins of both membranes span the lipid bilayer once or several times by a-helical stretches and their integration is usually mediated by uncleaved signal-anchor sequences. Proteins that are translocated across either membrane, collectively also termed secretory proteins, harbour cleavable N-terminal signal sequences. Prokaryotic and eukaryotic signal sequences have the same modular structure and are functionally...
Protein transport events occurring at the endoplasmic reticulum (ER) of eukaryotic cells and the cytoplasmic membrane of prokaryotic organisms share m...
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806,99 zł |
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Visceral Perception: Understanding Internal Cognition
ISBN: 9781441932907 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Author Gyorgy Adam maintains there is a type of sensory system active within the internal organs that appears to be, in some measure, independent of the traditional senses. Variously termed viscerosensory perception, internal perception, or internal cognition, this system operates largely outside of consciousness. Adam employs the extensive data he has gathered over many years to demonstrate how "hidden" internal signals originating in the alimentary tract, the cardiovascular system, and the kidneys may influence emotional states. Visceral Perception is the only comprehensive...
Author Gyorgy Adam maintains there is a type of sensory system active within the internal organs that appears to be, in some measure, independent of t...
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403,47 zł |
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Role of Proteases in the Pathophysiology of Neurodegenerative Diseases
ISBN: 9781441933607 / Angielski / Miękka / 302 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret. The breakdown part of protein turnover in vivo, particularly in nervous tissue, was such a subject in the past - it was difficult to measure and difficult to explore the mechanisms involved. For factors that influence protein metabolism, it was thought that protein content, function, and distribution are controlled only by the synthetic mechanisms that can supply the needed specificity and...
Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects fo...
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605,23 zł |
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RNA Binding Proteins: New Concepts in Gene Regulation
ISBN: 9781441949356 / Angielski / Miękka / 308 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. RNA binding proteins are an exciting area of research in gene regulation. A multitude of RNA-protein interactions are used to regulate gene expression including pre-mRNA splicing, polyadenylation, editing, transport, cytoplasmic targeting, translation and mRNA turnover. In addition to these post-transcriptional processes, RNA-protein interactions play a key role in transcription as illustrated by the life cycle of retroviruses. Unlike DNA, the structure of RNA is highly variable and conformationally flexible, thus creating a number of unique binding sites and the potential for complex...
RNA binding proteins are an exciting area of research in gene regulation. A multitude of RNA-protein interactions are used to regulate gene expression...
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806,99 zł |
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Reviews of Physiology, Biochemistry and Pharmacology 149
ISBN: 9783642057779 / Angielski / Miękka / 103 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. D. Kamimura, K. Ishihara, T. Hirano: IL-6 Signal Transduction and its Physiological Roles: The Signal Orchestration Model M. Tanaka and A. Miyajima: Oncostatin M, a Multifunctional Cytokine G.-J. van de Geijn, L.H.J. Aarts, S.J. Erkeland, J. Prasher, and I.P. Touw: Granulocyte Colony-Stimulating Factor and its Receptor in Normal Hematopoietic Cell Development and Myeloid Disease T. Hanada, I. Kinjyo, K. Inagaki-Ohara and A. Yoshimura: Negative Regulation of Cytokine Signaling by CES/SOCS Family Proteins and Their Roles in Inflammatory Diseases J. Kalesnikoff, L.M. Sly, M.R.... D. Kamimura, K. Ishihara, T. Hirano: IL-6 Signal Transduction and its Physiological Roles: The Signal Orchestration Model M. Tanaka and A. Miyaj... |
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605,23 zł |
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Plasma Membrane Redox Systems and Their Role in Biological Stress and Disease
ISBN: 9789048151349 / Angielski / Miękka / 334 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides a comprehensive treatment of the involvement of plasma membrane redox reactions in the origin and development of biological stress and disease. Thirteen chapters, provided by invited specialists, cover the role of plasma membrane redox systems in cell defence (of plant and animal cells), growth control, antioxidative defence reactions, development of tumour cells, entry of toxins and viruses, reduction and uptake of iron and nitrate, and development of atherosclerosis. Each of these chapters deals extensively with the most recent molecular and cell biological developments...
This book provides a comprehensive treatment of the involvement of plasma membrane redox reactions in the origin and development of biological stress ...
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605,23 zł |
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Philosophy, Psychology, and Psychologism: Critical and Historical Readings on the Psychological Turn in Philosophy
ISBN: 9789048163038 / Angielski / Miękka / 342 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Philosophy, Psychology, and Psychologism presents a remarkable diversity of contemporary opinions on the prospects of addressing philosophical topics from a psychological perspective. It considers the history and philosophical merits of psychologism, and looks systematically at psychologism in phenomenology, cognitive science, epistemology, logic, philosophy of language, philosophical semantics, and artificial intelligence. It juxtaposes many different philosophical standpoints, each supported by rigorous philosophical argument.
Philosophy, Psychology, and... Philosophy, Psychology, and Psychologism presents a remarkable diversity of contemporary opinions on the prospects of addressing phil...
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605,23 zł |
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Bone Metastasis and Molecular Mechanisms: Pathophysiology
ISBN: 9789048165636 / Angielski / Miękka / 308 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Patients with advanced breast or prostate cancers usually develop bone metastases. The principal complications resulting from metastatic bone disease are pain, spinal cord compression, pathologic fractures and bone marrow suppression. Improving the management of bone metastases is crucial to quality of life for patients with breast and prostate cancer. Advances in understanding of the molecular mechanisms underlying the pathophysiology of bone metastasis are driving the development of new therapeutic strategies. Patients with advanced breast or prostate cancers usually develop bone metastases. The principal complications resulting from metastatic bone disea... |
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605,23 zł |
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Cytokines and Colony Stimulating Factors: Methods and Protocols
ISBN: 9781617373183 / Angielski / Miękka / 478 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The immune system is a complex network in which different cell types and soluble factors interact to efficiently eliminate various kinds of microorganisms as well as aberrant cell clones. The roots of immunologic investigations reach far into the past. In 430 BC, Thucydides reported that survivors of the plague did not present a second time with similar symptoms. The first report of a successful immu- therapy was made by Edward Jenner in 1798 who found a protective effect of cowpox vaccination against human pox. Since then, much knowledge has been accumulated; today, investigations of the...
The immune system is a complex network in which different cell types and soluble factors interact to efficiently eliminate various kinds of microorgan...
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403,47 zł |
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Bone Regeneration and Repair: Biology and Clinical Applications
ISBN: 9781617372193 / Angielski / Miękka / 398 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.
This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and ...
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887,69 zł |
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Adrenal Disorders
ISBN: 9781617370298 / Angielski / Miękka / 424 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Adrenal Disorders, a panel of distinguished physicians and researchers select the most relevant new findings and integrate them into the existing body of clinical knowledge on adrenal pathologies. The book includes important reviews of disturbances in cortisol homeostasis, and new concepts regarding adrenal tumors and hereditary adrenal diseases. Also discussed are mineralocorticoids and the syndromes of mineralocortoid excess and aldosterone synthase deficiency. Authoritative and insightful, Adrenal Disorders provides physicians and scientists with a comprehensive, state-of-the-art...
In Adrenal Disorders, a panel of distinguished physicians and researchers select the most relevant new findings and integrate them into the existing b...
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887,69 zł |
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Reviews of Physiology, Biochemistry and Pharmacology 139
ISBN: 9783642084973 / Angielski / Miękka / 174 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this volume of Reviews of Physiology, Biochemistry and Pharmacology there a contributions by M.D. Swope, E. Lolis, F.Hofmann, L. Lacinova, N. Klugbauer, M. Hermann, P. Berger, S.S. Shen, J.S. Kim, M.E. Weksler, M. Hirsch-Kauffmann and M.Schweiger."
In this volume of Reviews of Physiology, Biochemistry and Pharmacology there a contributions by M.D. Swope, E. Lolis, F.Hofmann, L. Lacinova, N. Klugb...
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806,99 zł |
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Patho Phlash!: Pathophysiology Flash Cards
ISBN: 9780803624931 / Angielski / Other / 426 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Perfect for...
Rely on over 200 full-color flash cards for the most critical clinical information about common diseases and disorders. Color-coded by body system, these handy cards familiarize students with the great deal of pathophysiologic information they must master. Perfect for...
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159,50 zł |
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Ecto-Atpases: Recent Progress on Structure and Function
ISBN: 9780306455841 / Angielski / Twarda / 294 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Forty-one papers and three discussion sessions from the August 1996 workshop which premiered the results of the molecular cloning of potato apyrase showing five E-type ATPases from plants and microorganisms share consensus sequences found in human and murine CD39. The contributors demonstrated the u
Forty-one papers and three discussion sessions from the August 1996 workshop which premiered the results of the molecular cloning of potato apyrase sh...
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408,11 zł |
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Oxidative Stress in Skeletal Muscle
ISBN: 9783764358204 / Angielski / Twarda / 456 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Skeletal muscle consumes significant amounts of oxygen, and its oxygen flux increases significantly under conditions of exercise and muscle contraction. This makes the muscle vulnerable to oxidative stress since concomitantly with the increase of oxygen flow there is an increase of free oxygen radicals which are a byproduct of muscle respiration. A number of studies in the last decade have documented the involvement of free oxygen radicals in exercising muscles. The consequences of muscle oxidative stress have resulted mainly in increased muscle protein oxidation, elevation of lipid...
Skeletal muscle consumes significant amounts of oxygen, and its oxygen flux increases significantly under conditions of exercise and muscle contractio...
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cena:
408,11 zł |
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Cell Death in Reproductive Physiology
ISBN: 9780387983448 / Angielski / Twarda / 305 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An analysis of cell death in reproductive physiology. It examines topics such as the control of apoptosis in the uterus during decidualization and stern cell factor regulation of apoptosis in mouse primordial germ cells.
An analysis of cell death in reproductive physiology. It examines topics such as the control of apoptosis in the uterus during decidualization and ste...
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480,69 zł |
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Asthma
ISBN: 9781617371035 / Angielski / Miękka / 346 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Asthma has rapidly become one of the most common chronic illnesses of the Western world, and its prevalence continues to rise, with the proportion of patients with more severe diseases also increasing. Faced with this problem, more researchers are focusing on the causes, mechanisms, and pathophysiology of asthma. The major hopes are that more effective drugs will become available and that preventive measures can be instituted. Increasingly, molecular and cell bi- ogy approaches are being used to characterize and understand the mechanisms of the inflammatory process that is typical of the...
Asthma has rapidly become one of the most common chronic illnesses of the Western world, and its prevalence continues to rise, with the proportion of ...
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605,23 zł |
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Bone Research Protocols
ISBN: 9781617373213 / Angielski / Miękka / 450 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The last decade has seen a tremendous advance in our understanding of bone biology. The genes responsible for the majority of rare inherited bone disorders have been identified and much progress has been made in the identification of genes in polygenic disorders such as Paget s disease and complex multigene diseases such as osteoporosis. Transgenic technology has identified further genes, sometimes unexpectedly, with profound effects on bone. This wealth of new genetic information will undoubtedly lead to extensive cell biological studies to understand the mechanisms by which these gene...
The last decade has seen a tremendous advance in our understanding of bone biology. The genes responsible for the majority of rare inherited bone diso...
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cena:
475,94 zł |
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