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Turning Up the Heat on Pain: Trpv1 Receptors in Pain and Inflammation
ISBN: 9783764370800 / Angielski / Twarda / 249 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Vanilloids mediate their effects by selective agonism of an ion channel, the vanilloid receptor 1 (TRPV1). TRPV1 is a ligand-gated, non-selective, cation channel preferentially expressed in small-diameter, primary afferent neurons, including nociceptive sensory nerves. In addition to be activated by capsaicin and related vanilloids, TRPV1 responds to heat and extracellular acidification, and will integrate simultaneous exposures to these stimuli. The aim of this book is to summarize recent insights in the role of TRPV1 in pain and inflammation, and to discuss how modulation of this... Vanilloids mediate their effects by selective agonism of an ion channel, the vanilloid receptor 1 (TRPV1). TRPV1 is a ligand-gated, non-selective, ... |
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603,81 |
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From Basic Immunology to Immune-Mediated Demyelination
ISBN: 9788847000544 / Angielski / Twarda / 315 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, with particular emphasis on basic aspects of the regulation of immune responses during demyelinating disorders. The volume will be helpful to neuroimmunologists, but also to clinicians which will find a clear and concise understanding of the main features of neuroinflammatory disease.
This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage....
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805,10 |
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Neurodegeneration in Multiple Sclerosis
ISBN: 9788847003903 / Angielski / Twarda / 236 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic confidence and for monitoring the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy of cMRI to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is changing dramatically our understanding of how MS causes irreversible disability. In detail, there is an increasing... In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic confidence and f... |
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603,81 |
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Sex Differences in Lateralization in the Animal Brain
ISBN: 9789058230881 / Angielski / Twarda / 224 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Until recently, little account has been taken of sex differences in many research studies in psychiatry, medicine and physiology. Subjects of these research studies were mainly men, with most researchers using twice as many males as females in their studies. The need to take a sexually differentiated approach has led to the work described in this book, concerning detailed investigations into the correlations between functional asymmetry of the brain and sex.
Sex Differences in Lateralization in the Animal Brain is the first monograph summarizing the sexual specificity of functional... Until recently, little account has been taken of sex differences in many research studies in psychiatry, medicine and physiology. Subjects of these re...
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1053,01 |
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Understanding Brain and Mind: A Connectionist Perspective
ISBN: 9789810247928 / Angielski / Twarda / 252 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. How can we understand a system as complex as the brain? Does the brain use the same operational principles to control physical and mental activities? How can we incorporate in a model what we know and what we do not know about the brain? The connectionist model presented in this book provides tools for addressing such questions. Its nodes represent well-established biological facts combined with observations of the overall behaviours of the system. The model is based on comparing and contrasting brains, computers, and neural networks. It defines a framework for understanding the relationships...
How can we understand a system as complex as the brain? Does the brain use the same operational principles to control physical and mental activities? ...
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cena:
479,98 |
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Understanding Brain and Mind: A Connectionist Perspective
ISBN: 9789810247959 / Angielski / Miękka / 252 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. How can we understand a system as complex as the brain? Does the brain use the same operational principles to control physical and mental activities? How can we incorporate in a model what we know and what we do not know about the brain? The connectionist model presented in this book provides tools for addressing such questions. Its nodes represent well-established biological facts combined with observations of the overall behaviours of the system. The model is based on comparing and contrasting brains, computers, and neural networks. It defines a framework for understanding the relationships...
How can we understand a system as complex as the brain? Does the brain use the same operational principles to control physical and mental activities? ...
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254,68 |
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Theory of Cortical Plasticity
ISBN: 9789812387912 / Angielski / Miękka / 332 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Theory of Cortical Plasticity, Nobel Laureate Leon Cooper and his collaborators present a systematic development of the Bienenstock, Cooper and Munro (BCM) theory of synaptic plasticity, and discuss experiments that test both its assumptions and consequences. This insightful book provides an elegant analysis of theoretical structure in neuroscience research, and elucidates the role BCM theory has played in guiding research leading to our present understanding of the mechanisms underlying cortical plasticity. This book has been selected for coverage in: -CC / Physical, Chemical & Earth...
In Theory of Cortical Plasticity, Nobel Laureate Leon Cooper and his collaborators present a systematic development of the Bienenstock, Cooper and Mun...
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195,91 |
![Current Topics in Primate Vocal Communication Elke Zimmermann U. J]rgens J. Newman 9780306450648 Plenum Publishing Corporation](/9780306450648_current_topics_in_primate_vocal_communication.jpg "Current Topics in Primate Vocal Communication") |
Current Topics in Primate Vocal Communication
ISBN: 9780306450648 / Angielski / Twarda / 286 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. More than 25 years ago, the first major review of primate communication appeared (Altmann, 1967). Since then, information on the communicative abilities of primates increased rapidly, resulting, 15 years later, in the appearance of the first volume in which signaling systems were analyzed in a broader variety of primate groups within an evolutionary perspective (Snowdon, Brown and Petersen, 1982). Seven years later, the first volume dedicated solely to primate vocal communication appeared (Todt, Goedeking and Symmes, 1988) and another four years later a volume followed in which nonverbal...
More than 25 years ago, the first major review of primate communication appeared (Altmann, 1967). Since then, information on the communicative abiliti...
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603,81 |
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The Study of Dyslexia
ISBN: 9780306485312 / Angielski / Twarda / 289 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In long-ago 1999, the Dyslexia Institute and Plenum Press conceived a plan for two books which would gather the best of current knowledge and practice in dyslexia studies. This would benefit those but not only those many individuals who train with us, acquiring a postgraduate certificate and diploma with our higher education partner, the University of York. Since then, the century changed, the hinge of history creaked and Plenum was taken over by Kluwer Academic Publishers, but the first of the pair, Dyslexia in Practice, emerged quickly and on schedule (Townend and Turner, 2000). Written by...
In long-ago 1999, the Dyslexia Institute and Plenum Press conceived a plan for two books which would gather the best of current knowledge and practice...
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603,81 |
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The Ionotropic Glutamate Receptors
ISBN: 9780896034563 / Angielski / Twarda / 379 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The field of the excitatory amino acids was born when L-glutamate and L-aspartate were found to be potent convulsants (Hayashi, 1954), and were subsequently found to excite neurons directly (Curtis, Phillis, and Watkins, 1959). Although these studies initiated the hypothesis of glutamate-mediated neurotransmission, it was noted that the ubiquitous actions of glutamate could also reflect a general, nonspecific property of glutamate on neuronal mem branes. It was not until 20 years later that pharmacological, physiological, and biochemical studies provided convincing evidence for a...
The field of the excitatory amino acids was born when L-glutamate and L-aspartate were found to be potent convulsants (Hayashi, 1954), and were subseq...
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603,81 |
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The Mechanisms of Neuronal Damage in Virus Infections of the Nervous System
ISBN: 9783540676171 / Angielski / Twarda / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It has been recognized that viruses can induce neuronal damage by a variety of mechanisms. This volume summarizes the various ways that neurons can degenerate under the influence of viral infection, ranging from acute necrosis and virus-induced apoptosis to chronic damage in persistent infections. The mechanisms of neuronal latency are dealt with as well. The volume also includes chapters that review the chronic damage caused by viral proteins that interfere with differentiated functions of the neuron, including signalling by neurotransmitters and signal transduction by trophic factors. Other...
It has been recognized that viruses can induce neuronal damage by a variety of mechanisms. This volume summarizes the various ways that neurons can de...
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885,61 |
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Experimental Models of Multiple Sclerosis
ISBN: 9780387255170 / Angielski / Twarda / 902 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous system that affects about 350,000 individuals in the US, and many more around the world. The mechanism of this disease is largely unknown and there is no cure for it. However, there are several well-characterized experimental animal models that help us understand and speculate about potential mechanisms of pathology in this disease. Many of the experimental therapies designed for this disease rely on testing the drugs in animal models before using it in clinical trials. This book combines for the first... Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous system that affects about 350,000 individuals in the US, and... |
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805,10 |
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Advances and Technical Standards in Neurosurgery, Volume 31
ISBN: 9783211282533 / Angielski / Twarda / 290 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. AsanadditiontotheEuropeanpostgraduatetrainingsystemforyoung neurosurgeons, we began to publish in 1974 this series of Advancesand Technical Standards in Neurosurgery which was later sponsored by the EuropeanAssociationofNeurosurgicalSocieties. This series was ?rst discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathersoftheseriesbeingJeanBrihaye, BernardPertuiset, FritzLoewand HugoKrayenbuhl. ThuswereestablishedtheprinciplesofEuropean- operationwhich havebeenbornfromthe Europeanspirit, ?ourishedin theEuropeanAssociation,...
AsanadditiontotheEuropeanpostgraduatetrainingsystemforyoung neurosurgeons, we began to publish in 1974 this series of Advancesand Technical Standards ...
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603,81 |
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Toxin-Induced Models of Neurological Disorders
ISBN: 9780306446146 / Angielski / Twarda / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Tbis volume discusses and evaluates the use of neurotoxins to produce animal models of human neurodegenerative diseases. Tbe models presented use neuro toxins to induce some or most of the pathophysiological changes (including behavioral) that characterize the most studied motor neuron disorders and cogni tive disorders (dementia) in humans. Within the biomedical research community, there is little doubt about the utility of such models. But with increasing frequen cy, individuals concemed with animal rights question the validity of such models and argue that they actually produce no useful...
Tbis volume discusses and evaluates the use of neurotoxins to produce animal models of human neurodegenerative diseases. Tbe models presented use neur...
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402,53 |
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Animal Models of Neurological Disease, II: Metabolic Encephalopathies and Epilepsies
ISBN: 9780896032118 / Angielski / Twarda / 373 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further - search using animals is necessary and why animal models of psychiatric disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e-...
to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric dis...
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603,81 |
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Representation and Brain
ISBN: 9784431730200 / Angielski / Twarda / 368 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. How is information represented in the nervous system? How is that information manipulated and processed? These are some of the more important and challenging questions for neuroscientists and psychologists today. Understanding brain functions, especially the neural mechanisms of higher cognitive processes such as thinking, reasoning, judging, and decision making, are the subjects covered by the research in the chapters of this book. They describe recent progress in four major research areas: visual functions, motor functions, memory functions, and prefrontal functions. Readers will obtain an...
How is information represented in the nervous system? How is that information manipulated and processed? These are some of the more important and chal...
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603,81 |
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Handbook of the Neuroscience of Language
ISBN: 9780080453521 / Angielski / Twarda / 463 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the last ten years the neuroscience of language has matured as a field. Ten years ago, neuroimaging was just being explored for neurolinguistic questions, whereas today it constitutes a routine component. At the same time there have been significant developments in linguistic and psychological theory that speak to the neuroscience of language. This book consolidates those advances into a single reference. The Handbook of the Neuroscience of Language provides a comprehensive overview of this field. Divided into five sections, section one discusses methods and techniques... In the last ten years the neuroscience of language has matured as a field. Ten years ago, neuroimaging was just being explored for neurolinguistic ... |
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675,89 |
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Luria's Legacy in the 21st Century
ISBN: 9780195176704 / Angielski / Twarda / 208 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This is a collection of essays by leading neuropsychologists and cognitive neuroscientists to honor Alexander Romanovich Luria and to highlight the enduring impact of his legacy on cognitive neuroscience and clinical neuropsychology. A wide range of topics is covered, from functional neuroimaging in neuropsychology to bedside evaluation techniques. Several generations of neuropsychologists and cognitive neuroscientists are among contributors, including those who closely worked with Luria, their own students, and others influenced in their work by Luria's pioneering insights.
This is a collection of essays by leading neuropsychologists and cognitive neuroscientists to honor Alexander Romanovich Luria and to highlight the en...
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303,26 |
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Neurodegenerative Diseases: Molecular and Cellular Mechanisms and Therapeutic Advances
ISBN: 9780306452987 / Angielski / Twarda / 482 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book presents much of the exciting new information on mechanisms of neurodegenerative disorders that was presented at the XVth International Spring Symposium on Health Sciences at George Washington University in Washington, D.C. The organization of the symposium as weIl as the chapters within this book were based upon fundamental molecular and cellular mechanisms of neurodegeneration rather than upon different clinically defined disorders, in order to emphasize the commonality of cause rather than effect. The first part of the book is devoted to the relationships between selective...
This book presents much of the exciting new information on mechanisms of neurodegenerative disorders that was presented at the XVth International Spri...
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cena:
805,10 |
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Pituitary Tumors in Pregnancy
ISBN: 9780792374428 / Angielski / Twarda / 203 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pituitary adenomas account for 10-15% of all intracranial tumors and they frequently impair fertility. The development of medical and surgical therapy for such tumors has turned pregnancy into a reality for women harboring pituitary adenomas. However, gestation risks for both mother and fetus are still of concern for endocrinologists, gynecologists and pediatricians. This book intends to update knowledge on this topic, mainly regarding fertility restoration as well as gestational and post gestational management of patients with pituitary tumors.
Pituitary adenomas account for 10-15% of all intracranial tumors and they frequently impair fertility. The development of medical and surgical therapy...
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cena:
402,53 |
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