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AIDS Allergy and Rheumatology
ISBN: 9780896035027 / Angielski / Twarda / 102 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Leading clinical experts survey the latest information available on the key rheumatic and allergic issues that physicians face in treating the HIV-infected patient. The physicians focus on the rheumatologic and dermatologic manifestations of HIV-1 infection, which include arthritis, myopathies, vasculitis, sicca syndrome, other autoimmune phenomena, and psoriasis. They also examine the question of allergic reactions in HIV patients, including drug hypersensitivity, with special attention given to adverse reactions to trimethoprim-sulfamethoxazole, the most frequently prescribed...
Leading clinical experts survey the latest information available on the key rheumatic and allergic issues that physicians face in treating the HIV-inf...
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cena:
541,33 |
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Mhc Protocols
ISBN: 9780896035485 / Angielski / Twarda / 340 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The aim of MHC Protocols is to document protocols that can be used for the analysis of genetic variation within the human major histocompatibility complex (MHC; HLA region). The human MHC encompasses approximately 4 million base pairs on the short arm of chromosome 6 at cytogenetic location 6p21. 3. The region is divided into three subregions. The telomeric class I region contains the genes that encode the HLA class I molecules HLA-A, -B, and -C. The centromeric class II region contains the genes encoding the HLA class II molecules HLA-DR, -DQ, and -DP. In between is the class III region,...
The aim of MHC Protocols is to document protocols that can be used for the analysis of genetic variation within the human major histocompatibility com...
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cena:
836,62 |
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Autoimmune Reactions
ISBN: 9780896035508 / Angielski / Twarda / 438 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Autoimmune Reactions tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other "self" systems. The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discusses possible general mechanisms of autoimmune disease-e.g., molecular mimicry and dysfunctional antigen presentation-and their...
Autoimmune Reactions tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itse...
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cena:
772,78 |
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Therapeutic Interventions in the Complement System
ISBN: 9780896035874 / Angielski / Twarda / 260 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A team of expert investigators and clinical researchers comprehensively review complement's basic biology, its role in disease, methods to measure its activity, and strategies for its inhibition in patients. Each chapter focuses on a specific area of basic and applied complement biology, spelling out the activation pathways and complement receptors. Informative animal models are discussed in detail, including the relative values of each model and the important interspecies differences that can distort the interpretation of preclinical studies. The emphasis throughout is on the pros and cons...
A team of expert investigators and clinical researchers comprehensively review complement's basic biology, its role in disease, methods to measure its...
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cena:
541,33 |
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Molecular and Cellular Basis of Inflammation
ISBN: 9780896035959 / Angielski / Twarda / 338 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The study of inflammation has captured the interest of scholars since the earliest recorded history. Symbols identifying the cardinal signs of inflammation were uncovered in both Sanskrit and hieroglyphics (1). Since complete apprecia tion of the inflammatory process is underscored by the need for knowledge at both the cellular and molecular levels, academic inquiry in the area of inflammation has led, in many respects, the foray of current biomedical research. Molecular and Cellular Basis of Inflammation represents research from the cutting edge in the broad view of inflammation. The...
The study of inflammation has captured the interest of scholars since the earliest recorded history. Symbols identifying the cardinal signs of inflamm...
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cena:
1082,70 |
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Complement Methods and Protocols
ISBN: 9780896036543 / Angielski / Twarda / 259 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The complement system, first described more than a century ago, was for many years the ugly duckling of the immunology world, but no more. Complement in recent years has blossomed into a fascinating and fast moving field of immediate relevance to clinical scientists in fields as diverse as transplantation biology, virology, and inflammation. Despite its emergence from the shadows, complement retains an unwarranted reputation for being difficult. This impression derives in large part from the superficially complicated nomenclature, a relic of the long and tortuous process of unraveling the...
The complement system, first described more than a century ago, was for many years the ugly duckling of the immunology world, but no more. Complement ...
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cena:
610,90 |
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Immunotherapy for Infectious Diseases
ISBN: 9780896036697 / Angielski / Twarda / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Immunotherapy for Infectious Disease, Jeffrey M. Jacobson, MD, and a panel of leading researchers review the state-of-the-art for treating various infections-particularly HIV-by manipulating the immune system's response rather than by chemical drugs. The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels levels as a protection against infection. The review of the current state of anti-HIV immunotherapy covers...
In Immunotherapy for Infectious Disease, Jeffrey M. Jacobson, MD, and a panel of leading researchers review the state-of-the-art for treating various ...
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cena:
541,33 |
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Retroviral Immunology
ISBN: 9780896036758 / Angielski / Twarda / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Although there have been many books on HIV and AIDS, surprisingly little has been published that focuses on the immunology of retroviral infections in general, and HIV in particular. Retroviral Immunology: Immune Response and Restoration is the first book of its kind to address the most important aspects of the immunology of retroviruses, including not only the virus-specific immune responses, but also genetic and virologic factors modulating these responses. The book also deals directly with the emerging concept of immune restora tion in retroviral infections, a particularly important...
Although there have been many books on HIV and AIDS, surprisingly little has been published that focuses on the immunology of retroviral infections in...
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cena:
836,62 |
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Chemokines in Disease: Biology and Clinical Research
ISBN: 9780896037038 / Angielski / Twarda / 330 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Caroline Hebert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ranging from the effects of chemokines and their receptors in retroviral infections, to their role in inflammation, angiogenesis/angiostasis, and tumor cell biology. The book examines in detail fifteen recently identified chemokines and elucidates the role of chemokine function in vivo from animal experiments. Animal models are also used to explore how chemokines operate in a variety of chronic and acute inflammatory diseases and in noninflammatory...
Caroline Hebert and a panel of key experimentalists and clinical investigators comprehensively review the state-of-the-art in the chemokine field, ran...
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cena:
1082,70 |
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Combination Vaccines
ISBN: 9780896037175 / Angielski / Twarda / 279 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A diverse team of leading experts comprehensively review the complex biology of a wide variety of vaccine combinations, as well as the technical, clinical, and regulatory aspects of their development. Topics covered range from the use of immunological correlates of efficacy, rather than efficacy per se, for the evaluation and licensure of vaccine combinations, to preserving a stable immunogenic mixture in appropriate containers according to accepted regulatory standards. Discussed in detail are the trivalent influenza vaccine, the pneumococcal polysaccharide vaccine, the MMR vaccine, the DTP...
A diverse team of leading experts comprehensively review the complex biology of a wide variety of vaccine combinations, as well as the technical, clin...
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cena:
836,62 |
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Interleukin Protocols
ISBN: 9780896037380 / Angielski / Twarda / 443 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and belong to a broader family termed cytokines. Collectively these proteins are the key orchestrators of host defense and the response to tissue injury. There are currently 23 different interleukins (numbered from IL-1 to IL-23), although the full extent of the interleukin family will only become clear upon analysis of the human genome sequence. Most important, interleukins are central to the pathogenesis of a wide range of diseases that involve...
Interleukins are a family of proteins that regulate the maturation, diff- entiation, or activation of cells involved in immunity and inflammation, and...
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cena:
541,33 |
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Antigen Processing and Presentation Protocols
ISBN: 9780896037458 / Angielski / Twarda / 270 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Antigen processing and presentation, as a field, explores a broad range of protein interactions and functions, both intracellular (in the cytoplasm and in the endoplasmic reticulum) and at the cell surface (between T cells and MHC molecules). To investigate such a diverse array, it is necessary that biochemical, cell biology, and immunological techniques all be employed. The purpose of Antigen Processing and Presentation Protocols is therefore to detail the most up-to-date techniques being used in this burgeoning field. Such techniques include those used to question how MHC-binding peptides...
Antigen processing and presentation, as a field, explores a broad range of protein interactions and functions, both intracellular (in the cytoplasm an...
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cena:
515,17 |
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Cytokines and Autoimmune Diseases
ISBN: 9780896038561 / Angielski / Twarda / 422 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple...
Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in t...
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cena:
610,90 |
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Allergy Methods and Protocols
ISBN: 9780896038967 / Angielski / Twarda / 352 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Allergy: Methods and Protocols aims to assist the researcher in gaining insight into the molecular mechanisms involved in allergy by featuring an array of protocols. The protocols cover a range of disciplines including allergy, immunology, cell biology, and histology, and include methods to investigate the cellular response to allergens, cytokine profile, MHC restriction, and T regulatory cells. Allergy: Methods and Protocols aims to assist the researcher in gaining insight into the molecular mechanisms involved in allergy by featuring an a... |
cena:
610,90 |
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Cytokine Protocols
ISBN: 9780896039483 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During the last 30 years there has been a growing interest in cytokines as biological molecules able to regulate the most diverse functions in living org- isms, mainly at the level of cell-cell communication. Originally their definition was limited to the cells of the immune system (interleukins and lymphokines), but later that definition was extended to all cells, and their regulatory activity in such other processes as differentiation, apoptosis, angiogenesis, and wound he- ing has been now demonstrated. They comprise a group of small proteins (5-20 kDa) produced and released by cells in a...
During the last 30 years there has been a growing interest in cytokines as biological molecules able to regulate the most diverse functions in living ...
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cena:
541,33 |
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Cell Cycle Control and Dysregulation Protocols
ISBN: 9780896039490 / Angielski / Twarda / 185 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cell Cycle Control and Dysregulation Protocols focuses on emerging methodologies for studying the cell cycle, kinases, and kinase inhibitors. It addresses the issue of gene expression in vivo and in vitro, the analysis of cyclin-dependent kinase inhibitors, protein degradation mediated by the proteosome, the analysis of the transformed cell phenotype, and innovative techniques to detect apoptosis. Because there are already many manuals and protocols available, along with commercial kits and reagents, a variety of the more common techniques have not been included in our book. The protocols...
Cell Cycle Control and Dysregulation Protocols focuses on emerging methodologies for studying the cell cycle, kinases, and kinase inhibitors. It addre...
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cena:
407,25 |
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Superantigen Protocols
ISBN: 9780896039841 / Angielski / Twarda / 259 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Superantigen Protocols assembles experimental protocols that have proved useful for the study of superantigens. These techniques will allow researchers from various areas of cell biology, microbiology, immunology, biochemistry, and molecular biology to assess the physical characteristics and biological effects of well-known superantigens as well as of putative substances that might have superantigenic activities, and to explore therapies for superantig- induced effects. Microbial exotoxins have been studied for decades as virulence factors because of their pathogenic effects. The term...
Superantigen Protocols assembles experimental protocols that have proved useful for the study of superantigens. These techniques will allow researcher...
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cena:
541,33 |
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Killer Lymphocytes
ISBN: 9781402032691 / Angielski / Twarda / 361 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The existence of a unique kind of immune cell the killer lymphocyt- which destroys other cells in a highly specific manner, has fascinated immunologists for almost half a century. How do these cells, whose precursors have lived in communal harmony with their host, decide that some of their cohabitants must die? And how do they kill them? The definition of killer lymphocytes came from discovery of their roles in a wide range of in vivo phenomena such as transplant rejection, virus infection and its related immunopathologies, and anti-tumor responses. Yet for the most part almost everything we...
The existence of a unique kind of immune cell the killer lymphocyt- which destroys other cells in a highly specific manner, has fascinated immunologis...
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cena:
610,90 |
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Killer Lymphocytes
ISBN: 9781402065637 / Angielski / Miękka / 361 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The existence of a unique kind of immune cell the killer lymphocyt- which destroys other cells in a highly specific manner, has fascinated immunologists for almost half a century. How do these cells, whose precursors have lived in communal harmony with their host, decide that some of their cohabitants must die? And how do they kill them? The definition of killer lymphocytes came from discovery of their roles in a wide range of in vivo phenomena such as transplant rejection, virus infection and its related immunopathologies, and anti-tumor responses. Yet for the most part almost everything we...
The existence of a unique kind of immune cell the killer lymphocyt- which destroys other cells in a highly specific manner, has fascinated immunologis...
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cena:
610,90 |
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Immunology and Infectious Disease
ISBN: 9781402073076 / Angielski / Twarda / 276 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Individualized dosing regimens specific to the patient, infection, bacteria, and antibiotic can optimize outcome. Integration of pharmacokinetic and pharmacodynamic data, called dual individualization, can be accomplished through the use of AUIe. AUIC dosing has been shown to predict bacteriological outcomes, hasten clinical outcomes, reduce the emergence of resistance, and be cost-effective. MPC dosing has been shown to predict the emergence of resistant submutants. AUIC and MPC information can provide guidance as to when low doses can be used, and when higher concentrations are required....
Individualized dosing regimens specific to the patient, infection, bacteria, and antibiotic can optimize outcome. Integration of pharmacokinetic and p...
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cena:
541,33 |
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