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Immunsystem Und Infektiologie
ISBN: 9783662078662 / Niemiecki / Miękka / 428 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Die neuerliche weltweite Zunahme von Infektionserkrankungen, Veranderungen der Resistenz von Erregern sowie unser zunehmendes Verstandnis der Mechanismen immunologischer Reaktionen verleihen diesem Band gerade jetzt hohe Aktualitat. Der thematische Schwerpunkt wird auf die Darstellung der Pathologie des Immunsystems einschliesslich angeborener Immundefekte, chemotherapieresistenter Erreger, den Impfschutz, die molekulargenetischen Grundlagen der Allergie sowie die erworbene Immunschwache gelegt. Den inhaltlichen Schwerpunkt der einzelnen Kapitel bildet die Darstellung der molekularen Ursachen...
Die neuerliche weltweite Zunahme von Infektionserkrankungen, Veranderungen der Resistenz von Erregern sowie unser zunehmendes Verstandnis der Mechanis...
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413,81 |
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Radiolabeled Monoclonal Antibodies for Imaging and Therapy
ISBN: 9781468455403 / Angielski / Miękka / 876 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The advent of hybridoma technology leading to the successful produc tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations. These highly specific reagents have essentially replaced the polysera of the earlier days. The successful demonstration of the many wide ranging capabilities of the monoclonal antibody technique has already begun to exert an enormous impact on diverse areas of research in basic science and medicine. In particular, the potential of monoclonal...
The advent of hybridoma technology leading to the successful produc tion of monoclonal antibodies against a variety of tumor-associated antigens has, ...
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603,81 |
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The Sepsis Text
ISBN: 9781475783346 / Angielski / Miękka / 848 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the culmination of decades of basic and applied research by innovative researchers and clinical investigators worldwide. The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology; monitoring systems; general...
This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the ...
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cena:
805,10 |
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Endogenous Adp-Ribosylation
ISBN: 9783319107707 / Angielski / Twarda / 213 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections: - Evolution and detection of endogenous ADP-ribosylation - ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs) - ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs) The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing... This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into t... |
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402,53 |
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Advances in Transplant Dermatology: Clinical and Practical Implications
ISBN: 9783319124445 / Angielski / Twarda / 117 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commentary is provided on the emerging role of viruses in transplant dermatology, the management of skin disease secondary to transplant medication, sunscreen use in transplant recipients, the role of revision of immunosuppression, and advances in photodynamic therapy. The latest staging and management criteria for high-risk squamous cell carcinoma and the implications for clinical practice are then analyzed. Finally, the management of other cutaneous...
This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commen...
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402,53 |
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Mitochondrial Medicine: Mitochondrial Metabolism, Diseases, Diagnosis and Therapy
ISBN: 9789400786905 / Angielski / Miękka / 409 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Mitochondrial Medicine is a relatively new area where several disciplines from basic science to clinical medicine converge. Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. A primary feature of mitochondrial dysfunction is impaired cellular bioenergetics. This book is based upon extensive data gathered over 30 years of clinical and experimental research. Internationally recognized authors share their experience and state-of-the-art knowledge in various fields of their... Mitochondrial Medicine is a relatively new area where several disciplines from basic science to clinical medicine converge. Mitochondrial medicine ... |
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805,10 |
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Immunologic Signatures of Rejection
ISBN: 9781489982438 / Angielski / Miękka / 353 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book discusses the mechanisms leading to immune-mediated tissue rejection following the hypothesis that independent of the disease process the final effector mechanism is shared by most (but not all) pathologies and it is relatively simple. The book covers evidence gathered to support the thesis by studies performed in humans during rejection or in experimental models and will focus particularly (but not exclusively) on the analysis of the rejected tissue rather than the systemic circulation. Several disease processes are discussed including example of chronic inflammatory process...
This book discusses the mechanisms leading to immune-mediated tissue rejection following the hypothesis that independent of the disease process the fi...
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cena:
603,81 |
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Malignant Effusions: Pleuritis, Ascites, Pericardites
ISBN: 9789400798694 / Angielski / Miękka / 154 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Malignant effusions (pleurites, ascites and pericarditis) are some of the most frequent manifestations of dissemination process of malignant tumors. Accumulation of the malignant fluid in serous cavities results in impairment of respiratory and cardiac functions, however long-term evacuation of the fluid leads to severe disorders of homeostasis that may directly cause the patient s death. The aim of this comprehensive book is to provide detailed information of pathogenesis and management of malignant effusions. The current book focuses on three of these categories: pleuritis, acsites and...
Malignant effusions (pleurites, ascites and pericarditis) are some of the most frequent manifestations of dissemination process of malignant tumors. A...
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603,81 |
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In Vivo Models of HIV Disease and Control
ISBN: 9781489973320 / Angielski / Miękka / 436 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV. Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey,... An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between... |
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603,81 |
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Opportunities and Challenges of the Therapies Targeting CNS Regeneration
ISBN: 9783642421488 / Angielski / Miękka / 186 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The therapeutic options for the treatment of multiple sclerosis (MS) and other neurodegenerative and traumatic diseases such as spinal cord injury, Alzheimer s, Parkinson s disease, etc., have undergone enormous progress over recent years. Despite these encouraging developments, available therapies are only partially effective, and the ultimate goal is still far from being attained. Improved understanding of the cellular and molecular mechanisms of the pathogenesis of neurodegeneration and demyelination has led to a variety of new therapeutic targets and approaches. In addition to modulation...
The therapeutic options for the treatment of multiple sclerosis (MS) and other neurodegenerative and traumatic diseases such as spinal cord injury, Al...
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cena:
402,53 |
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Chronic Viral and Inflammatory Cardiomyopathy
ISBN: 9783642421433 / Angielski / Miękka / 370 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Following its tradition of promoting novel areas of scienti?c discourse, the Ernst Schering Research Foundation (ESRF) hosted this workshop on chronic viral and in?ammatory cardiomyopathy. In late October 2004, scientists from Canada, Germany, the Georgian Republic, Great Britain, Italy, Japan, the Netherlands, Israel, Sweden, and the United States ga- ered in Berlin to discuss their concepts, hypotheses, and latest ?ndings on myocarditis and cardiomyopathy. This expert meeting was held in cooperation with the German - search Foundation, which in the same year had supported transregional...
Following its tradition of promoting novel areas of scienti?c discourse, the Ernst Schering Research Foundation (ESRF) hosted this workshop on chronic...
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603,81 |
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Influenza Virus Sialidase - A Drug Discovery Target
ISBN: 9783034807791 / Angielski / Miękka / 178 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Influenza continues to be an ongoing problem despite the existence of vaccines and drugs. Disease outbreaks can occur relatively quickly as witnessed with the recent emergence of the influenza virus A/H1N1 pandemic. The development of new anti-influenza drugs is thus a major challenge. This volume describes all aspects of the virus structure and function relevant to infection. The focus is on drug discovery of inhibitors to the enzyme sialidase, which plays a key role in the infectious lifecycle of the virus. Following an overview of the influenza virus, the haemagglutinin, the interactions...
Influenza continues to be an ongoing problem despite the existence of vaccines and drugs. Disease outbreaks can occur relatively quickly as witnessed ...
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603,81 |
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The Immunological Barriers to Regenerative Medicine
ISBN: 9781489999320 / Angielski / Miękka / 334 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume offers an analysis of the scale and nature of the immunological issues facing regenerative medicine, drawing on the expertise of laboratories around the world who have taken up the challenge of applying their expertise in immunology to the vagaries of stem cell biology. In Part I, we explore the extent to which the principles of allograft rejection, learned over several decades from our experiences of whole organ transplantation, apply within the unique context of cell replacement therapy. Part II discusses various innovative ways of addressing the issues of immunogenicity, while,...
This volume offers an analysis of the scale and nature of the immunological issues facing regenerative medicine, drawing on the expertise of laborator...
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cena:
623,94 |
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Neural-Immune Interactions in Brain Function and Alcohol Related Disorders
ISBN: 9781489995780 / Angielski / Miękka / 588 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research....
Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuro...
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cena:
805,10 |
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The DNA Damage Response: Implications on Cancer Formation and Treatment
ISBN: 9789400779952 / Angielski / Miękka / 449 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The ?eld of cellular responses to DNA damage has attained widespread recognition and interest in recent years commensurate with its fundamental role in the ma- tenance of genomic stability. These responses, which are essential to preventing cellular death or malignant transformation, are organized into a sophisticated s- tem designated the "DNA damage response". This system operates in all living organisms to maintain genomic stability in the face of constant attacks on the DNA from a variety of endogenous by-products of normal metabolism, as well as exogenous agents such as radiation and...
The ?eld of cellular responses to DNA damage has attained widespread recognition and interest in recent years commensurate with its fundamental role i...
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603,81 |
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Sugar Chains: Decoding the Functions of Glycans
ISBN: 9784431553809 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological...
This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of prot...
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cena:
402,53 |
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The Hepatitis B and Delta Viruses
ISBN: 9781621820888 / Angielski / Twarda / 363 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Despite the availability of an effective vaccine for hepatitis B, hundreds of millions of people worldwide are infected with the hepatitis B virus (HBV). This virus can cause serious liver damage and cancer in chronically infected patients. Hepatitis delta virus (HDV), a satellite of HBV, can exacerbate the disease.
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines all aspects of HBV and HDV infections and their management. Contributors discuss the HBV and HDV life cycles, their unique characteristics (e.g., the formation... Despite the availability of an effective vaccine for hepatitis B, hundreds of millions of people worldwide are infected with the hepatitis B virus (HB...
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cena:
485,03 |
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Viral Genome Replication
ISBN: 9781489984685 / Angielski / Miękka / 636 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Currently, there is no single source that permitscomparisonof the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our parti- lar system, missing outon theopportunityto de neunifyingthemesin viralgenome replication or bene t from the advances in other systems. For example, extraor- nary biologicaland experimentalparadigmsthat have been established overthe past 5 years for the DNA replication systems of bacteriophage T4 will likely be of great value to anyone interested...
Currently, there is no single source that permitscomparisonof the factors, elements, enzymes and/or mechanisms employed by different classes of viruse...
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cena:
805,10 |
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Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules
ISBN: 9781489986443 / Angielski / Miękka / 274 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the... This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other ... |
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603,81 |
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GI Microbiota and Regulation of the Immune System
ISBN: 9781489988164 / Angielski / Miękka / 149 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The idea that the microbial communities within the GI tract have a profound influence on general human health actually originated with Russian scientist Elie Metchnikov at the turn ofthe last century. Also known as the "fatherofimmunol ogy," Metchnikovbelievedthat putrefactivebacteriain the gut were responsible for enhancing the aging process. He theorized that ingestion ofhealthy bacteria found in fermented foods could counteract toxic bacteria and was the key to good health. His theories concerning good bacteria and health can be found in his treatise "The ProlongationofLife: Optimistic...
The idea that the microbial communities within the GI tract have a profound influence on general human health actually originated with Russian scienti...
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cena:
603,81 |
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