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Cancer Immunology and Immunotherapy
ISBN: 9783642267888 / Angielski / Miękka / 306 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines...
The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance ...
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Sphingolipids: Basic Science and Drug Development
ISBN: 9783709113677 / Angielski / Twarda / 259 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in...
Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. Th...
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The Molecular Immunology of Complex Carbohydrates --2
ISBN: 9781461354697 / Angielski / Miękka / 640 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. I organized this symposium, "Molecular Immunology of Complex Carbohydrates-2 (MICC-2)," at the Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan th between August 28-September 2, 1999, as a satellite meeting of the 15 International Glycoconjugate Conference (held August 22-27 in Tokyo, Japan). I also held a Taiwan- Canada Glycobiology Workshop after this meeting at the Institutes of Biological Chemistry and Chemistry. To promote glycobiology in Taiwan, I offered a Complexs Carbohydrate & Medicine-2 workshop at the Glyco- Research Laboratory, College of Medicine, Chang- Gung...
I organized this symposium, "Molecular Immunology of Complex Carbohydrates-2 (MICC-2)," at the Institute of Biological Chemistry, Academia Sinica, Tai...
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Coronaviruses and Arteriviruses
ISBN: 9781461374329 / Angielski / Miękka / 826 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Coronaviruses and arteriviruses have emerged as major virus families relevant in ani mal and human health. The order Nidovirales, which includes the Coronaviridae and Ar teriviridae, was recognized by the International Committee for the Taxonomy of Viruses (ICTV) in 1996 based on the striking features common to the two virus families. In accord ance with this decision, the organizers of the coronavirus meeting, held every three years since 1980, invited colleagues working with both virus families to attend the VIIth Interna tional Symposium on Coronaviruses and Arteriviruses, held in Segovia,...
Coronaviruses and arteriviruses have emerged as major virus families relevant in ani mal and human health. The order Nidovirales, which includes the C...
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Natriuretic Peptides in Health and Disease
ISBN: 9781461284413 / Angielski / Miękka / 337 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A comprehensive, state-of-the-art review of the biochemistry, molecular and cellular biology, pharmacology, physiology, and pathology of natriuretic peptides. Written by the foremost researchers in the field, the reviews range from describing the actions of these peptides on the kidney, adrenal gland, vasculature, and brain, to their effects on immune regulation, reproduction, and cell growth. Special attention is given to the potential involvement of these hormones in clinical pathology and to their possible therapeutic use. Especially enlightening is the first-time review of molecular...
A comprehensive, state-of-the-art review of the biochemistry, molecular and cellular biology, pharmacology, physiology, and pathology of natriuretic p...
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Clinical Aspects of Interferons
ISBN: 9781461289777 / Angielski / Miękka / 366 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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Immune Regulation
ISBN: 9781461293903 / Angielski / Miękka / 392 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Leukocyte culture conferences have a long pedigree. This volume records some of the scientific highlights of the 16th such annual con ference, and is a witness to the continuing evolution and popularity of leukocyte culture and of immunology. There is strong evidence of the widening horizons of immunology, both technically, with the obviously major impact of molecular biology into our understanding of cellular processes, and also conceptually. Traditionally, the 'proceedings' of these conferences have been published. But have the books produced really recorded the major part of the...
Leukocyte culture conferences have a long pedigree. This volume records some of the scientific highlights of the 16th such annual con ference, and is ...
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International Symposium: Retroviruses and Human Pathology
ISBN: 9781461293965 / Angielski / Miękka / 557 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line. of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological...
For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of hu...
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Advances in DNA Damage and Repair: Oxygen Radical Effects, Cellular Protection, and Biological Consequences
ISBN: 9781461372073 / Angielski / Miękka / 511 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This volume covers the most recent developments in this research field and contains contributions from scientists working in various fields. In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This volume ... |
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Immunotoxicology and Risk Assessment
ISBN: 9781475781885 / Angielski / Miękka / 382 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to toxicologists because it will incorporate new guidelines that the EPA is bringing out later this year for all chemicals regulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each chapter focus on data from both...
This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on ha...
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Frontiers in Microbiology: From Antibiotics to AIDS
ISBN: 9789401080064 / Angielski / Miękka / 314 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The International Symposium on Frontiers in Microbiology has been de dicated to Prof. P. De Somer, whom I succeeded shortly after his death on 17 June 1985 as Rector of this now more than 560-year old University. When Prof. De Somer became the head of the University he started to remodel it, giving our old Alma Mater a more transparent administrative structure, strengthening its scientific and cultural autonomy, and establishing close links with the most prestigious national and foreign institutions. This made De Somer to one of the greatest, if not the greatest, of rectors in the history of...
The International Symposium on Frontiers in Microbiology has been de dicated to Prof. P. De Somer, whom I succeeded shortly after his death on 17 June...
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Monoclonal Antibodies to Receptors: Probes for Receptor Structure and Funtcion
ISBN: 9789401089555 / Angielski / Miękka / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Receptor specific antibodies are excellent probes for a wide range of biological investigations on receptor structure and function. The hybridoma technology (Kohler and Milstein, 1975) has inevitably had a major impact on this field with most of the better known receptors now identified with monoclonal antibodies. This volume of the Receptors and Recognition series provides reviews of recent developments in this field and emphasizes in particular the new opportunities afforded by the judicious application of monoclonal reagents. It is assumed that most readers will be familiar with the now...
Receptor specific antibodies are excellent probes for a wide range of biological investigations on receptor structure and function. The hybridoma tech...
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Renal Transplantation: Sense and Sensitization
ISBN: 9789401737395 / Angielski / Miękka / 312 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In 1986, the Committee of Experts on Blood Transfusion and Immunohae- tology of the Council of Europe chose for their Programme of Co-ordinated Research "An investigation of the procurement and sharing of transplantable organs for potential recipients who are highly sensitized to HLA-antigens". This topic was of common concern to all centres practising renal transplan- tion. The terms of reference of the study were: To estimate the number of patients who are virtually "untransplantable" because of high sensitization in each European country. To study the nature of immunization in terms of the...
In 1986, the Committee of Experts on Blood Transfusion and Immunohae- tology of the Council of Europe chose for their Programme of Co-ordinated Resear...
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Metalloproteinases as Targets for Anti-Inflammatory Drugs
ISBN: 9783034897242 / Angielski / Miękka / 207 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.
This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular the...
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Platelet-Activating Factor and Related Lipid Mediators 2: Roles in Health and Disease
ISBN: 9781489901811 / Angielski / Miękka / 401 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the last decade, research on platelet-activating factor (PAF) has expanded exponentially. Previous conferences on PAF in Paris, 1983, and the subsequent conferences in Gatlinburg, Ten- nessee, Tokyo, Snowbird, Utah, and Berlin, at three-yearly intervals, have chronicled the devel- opments in the field ofPAF. This volume records the proceedings of the Fifth International Con- gress on PAF and Related Lipid Mediators, held at the Free University Medical Hospital Ben- jamin Franklin in Berlin, from September 12-16, 1995. We are very much indebted to Free Uni- versity Berlin for providing...
In the last decade, research on platelet-activating factor (PAF) has expanded exponentially. Previous conferences on PAF in Paris, 1983, and the subse...
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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2
ISBN: 9781489902207 / Angielski / Miękka / 358 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 7th International Symposium on Platinum and other metal coordination compounds in Cancer Chemotherapy, ISPCC '95, organized by the European Cancer Centre, was held in Amsterdam, the Netherlands, March 1-4, 1995. As with previous ISPCC meetings, the goal of ISPCC '95 was to bring together c1inicians, clinical investigators, scientists, and laboratory workers from many disciplines to promote further collaboration and cooperation in the development of new platinum and other metal coordination compounds as weil as in new ways to use 'c1assical' drugs as cisplatin and carboplatin in the...
The 7th International Symposium on Platinum and other metal coordination compounds in Cancer Chemotherapy, ISPCC '95, organized by the European Cancer...
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Activators and Inhibitors of Complement
ISBN: 9789401052245 / Angielski / Miękka / 239 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The complement system is a group of proteins which plays a major role in the processing and removal of microorganisms and tissue breakdown products from the circulation and extracellular spaces. The system is activated by a wide range of targets, and activation leads to the production of opsonins, chemotaxis of granulocytes, cell lysis and other biological activities. Inappropriate overactivation of the system contributes to inflammatory tissue damage in the host, while inadequate activation leads to accumulation of immune complexes and other debris in the circulation, and susceptibility to...
The complement system is a group of proteins which plays a major role in the processing and removal of microorganisms and tissue breakdown products fr...
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Cancer Vaccines: Methods and Protocols
ISBN: 9781493903443 / Angielski / Twarda / 569 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cancer Vaccines: Methods and Protocols explores the manipulation and modification of immune cells, the manipulation and modification of tumor cells as well as the manipulation of immune/tumor interactions and various delivery mechanisms, with the overall end goal of evoking a tumor-specific response and overcoming the immuno-evasive mechanisms employed by the tumor cells. This detailed volume also covers the subject of cancer vaccines in a more global sense with its section on the advances, challenges, and future of cancer vaccines. Written in the highly successful Methods in... Cancer Vaccines: Methods and Protocols explores the manipulation and modification of immune cells, the manipulation and modification of tumo... |
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Tumor-Induced Immune Suppression: Mechanisms and Therapeutic Reversal
ISBN: 9781489980557 / Angielski / Twarda / 464 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor... Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of... |
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The Complement System: Novel Roles in Health and Disease
ISBN: 9781475779288 / Angielski / Miękka / 565 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent...
As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted...
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cena:
805,10 |
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