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The Politics of Personalised Medicine
ISBN: 9780521602655 / Angielski / Miękka / 216 str. This book applies a social science perspective to an examination of issues that arise in clinical practice as a result of drug development linked to genetic testing. These include the social context within which new drugs undergo trials and the related attitudes and expectations of clinicians and patients. Two case studies illustrate the arguments--one on aspects of Alzheimer's disease, and the other on the drug Herceptin which is used in the treatment of breast cancer.
This book applies a social science perspective to an examination of issues that arise in clinical practice as a result of drug development linked to g...
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cena:
283,31 zł |
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Cancer Vaccines and Immunotherapy
ISBN: 9780521622639 / Angielski / Twarda / 296 str. Rapid progress in the definition of tumor antigens, and improved immunization methods, bring effective cancer vaccines within reach. In this wide-ranging survey, leading clinicians and scientists review therapeutic cancer vaccine strategies against a variety of diseases and molecular targets. Intended for an interdisciplinary readership, their contributions cover the rationale, development, and implementation of vaccines in human cancer treatment, with specific reference to cancer of the cervix, breast, colon, bladder, and prostate, and to melanoma and lymphoma. They review target...
Rapid progress in the definition of tumor antigens, and improved immunization methods, bring effective cancer vaccines within reach. In this wide-rang...
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cena:
584,43 zł |
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The Politics of Personalised Medicine: Pharmacogenetics in the Clinic
ISBN: 9780521841771 / Angielski / Twarda / 216 str. This book applies a social science perspective to an examination of issues that arise in clinical practice as a result of drug development linked to genetic testing. These include the social context within which new drugs undergo trials and the related attitudes and expectations of clinicians and patients. Two case studies illustrate the arguments--one on aspects of Alzheimer's disease, and the other on the drug Herceptin which is used in the treatment of breast cancer.
This book applies a social science perspective to an examination of issues that arise in clinical practice as a result of drug development linked to g...
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cena:
409,10 zł |
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Cancer Doctor
ISBN: 9780595360109 / Angielski / Miękka / 248 str. "Students and house staff officers are lucky when one of their professors takes the time to discuss with them how he/she tells a bad diagnosis to a new patient. This is how I advise them to handle it: 'Take a chair or sit on the edge of the bed if need be and touch a hand. That will comfort the patient. And don't think for a minute that men do not appreciate that gesture; they do. Unless the patient decides differently, it is better when the spouse, a close member of the family or a friend is present. Remember that after you leave the room, it will be awfully lonely for the patient. Tell the...
"Students and house staff officers are lucky when one of their professors takes the time to discuss with them how he/she tells a bad diagnosis to a ne...
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cena:
81,90 zł |
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Cancer Doctor
ISBN: 9780595673148 / Angielski / Twarda / 248 str. "Students and house staff officers are lucky when one of their professors takes the time to discuss with them how he/she tells a bad diagnosis to a new patient. This is how I advise them to handle it: 'Take a chair or sit on the edge of the bed if need be and touch a hand. That will comfort the patient. And don't think for a minute that men do not appreciate that gesture; they do. Unless the patient decides differently, it is better when the spouse, a close member of the family or a friend is present. Remember that after you leave the room, it will be awfully lonely for the patient. Tell the...
"Students and house staff officers are lucky when one of their professors takes the time to discuss with them how he/she tells a bad diagnosis to a ne...
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cena:
122,96 zł |
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Adjuvant Therapy of Breast Cancer
ISBN: 9780792316565 / Angielski / Twarda / 464 str. The results of randomized trials evaluating the use of early or adjuvant systemic treatment for patients with resectable breast cancer provide an eloquent rebuttal to those who would argue that we have made no progress in the treatment of cancer. Many of the tumors that we have been most successful in curing with chemotherapy and other newer forms of treatment are relatively uncommon. In contrast, breast cancer continues to be the single most common malignancy among women in the western world, is increasingly a cause of death throughout Asia and Third-World countries, and remains one of the...
The results of randomized trials evaluating the use of early or adjuvant systemic treatment for patients with resectable breast cancer provide an eloq...
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cena:
1370,21 zł |
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Clinical Drug Trials and Tribulations, Revised and Expanded
ISBN: 9780824703141 / Angielski / Twarda / 368 str. This title comprehensibly addresses the day-to-day challenges of drug development with a contemporary assessment of the areas affecting the conduction of non-clinical and clinical studies.
This title comprehensibly addresses the day-to-day challenges of drug development with a contemporary assessment of the areas affecting the conduction...
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cena:
757,10 zł |
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Bioadhesive Drug Delivery Systems: Fundamentals, Novel Approaches, and Development
ISBN: 9780824719951 / Angielski / Twarda / 670 str. This is a review of the methods for characterizing bioadhesive materials and for improving vehicle targeting and uptake - offering possibilities for reformulating existing compounds to create new pharmaceuticals at lower development costs. It evaluates the unique carrier characteristics of bioadhesive polymers and their power to enhance localization of delivered agents, local bioavailability, and drug absorption and transport.
This is a review of the methods for characterizing bioadhesive materials and for improving vehicle targeting and uptake - offering possibilities for r...
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cena:
832,82 zł |
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Chemotherapy for Gynecological Neoplasms: Current Therapy and Novel Approaches
ISBN: 9780824754181 / Angielski / Twarda / 600 str. Compiling an authoritative collection of research, recommendations, and guidelines from a highly regarded team of experts, this reference promotes a clear understanding of the chemotherapeutic management of cancer in each organ site of the lower female genital tract including the ovaries, fallopian tubes, uterus, vulva, and vagina.
Compiling an authoritative collection of research, recommendations, and guidelines from a highly regarded team of experts, this reference promotes a c...
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cena:
959,00 zł |
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Antimicrobial Therapy in Abdominal Surgery: Precepts and Practices
ISBN: 9780849342691 / Angielski / Twarda / 105 str. Over the past 50 years, important developments have taken place in surgical and antimicrobial aspects of the management of intestinal surgery and intra-abdominal sepsis. Many new pathogens like Clostridium difficile, Helibacter and Ruminococcus have been described, and many new beta-lactam drugs and quinolones have been introduced. Immunological aspects such as T cell factors and interleukins have been shown to play an important role in the pathogenesis of intra-abdominal sepsis. Important new pieces of surgical hardware, sutures, and surgical glues to salvage solid organs were added to the...
Over the past 50 years, important developments have taken place in surgical and antimicrobial aspects of the management of intestinal surgery and intr...
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cena:
1034,71 zł |
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Platinum-Based Drugs in Cancer Therapy
ISBN: 9780896035997 / Angielski / Twarda / 341 str. Leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair and replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the...
Leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining...
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cena:
915,56 zł |
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Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery: Electrically Mediated Delivery of Molecules to Cells
ISBN: 9780896036062 / Angielski / Twarda / 497 str. Pulsed electric fields have been applied to living systems in vitro for a host of delivery applications since the early 1980s. It has been established that the primary effect that electrical treatment has on cells is an induced increase in the permeability of membranes to exogenous molecules. This state of increased permeability was noted to be temporary and could be induced with little or no effect on cell viability. This physical phenomenon was termed electroporation. Numerous published studies have shown that electroporation can be applied to any cell type. These studies also exploited the...
Pulsed electric fields have been applied to living systems in vitro for a host of delivery applications since the early 1980s. It has been established...
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cena:
688,23 zł |
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Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery
ISBN: 9780896036703 / Angielski / Twarda / 396 str. Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and...
Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the late...
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cena:
1006,49 zł |
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Antiestrogens and Antiandrogens
ISBN: 9780896036734 / Angielski / Twarda / 420 str. In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormonal treatments, assess the actions of new and established agents, and illustrate the new applications of hormonal chemoprevention for breast cancer. Topics range from preclinical and clinical antiestrogens to the inhibition of estrogen synthesis and the effects of androgen withdrawal. A wide variety of proven and new agents are discussed-antiestrogens, including aromatase inhibitors (anastrozole, letrozole, and others), SERMs (tamoxifen,...
In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormo...
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cena:
1138,38 zł |
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Regional Chemotherapy: Clinical Research and Practice
ISBN: 9780896037298 / Angielski / Twarda / 366 str. Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease. These authorities present a critical analysis of both the rationale and limitations of regional therapy and discuss potential clinical trials designed to explain the effectiveness of this method of therapy in special settings. Their presentations describe many exciting and innovative strategies for using regional drug delivery in anticancer therapy, including coverage of such areas...
Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antine...
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cena:
824,63 zł |
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Drug Delivery Systems in Cancer Therapy
ISBN: 9780896038882 / Angielski / Twarda / 390 str. Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have...
Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors re...
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cena:
1006,49 zł |
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Clinically Relevant Resistance in Cancer Chemotherapy
ISBN: 9781402072000 / Angielski / Twarda / 380 str. Over the last several decades, the introduction of new chemotherapeutic drugs and drug combinations has resulted in increased long term remission rates in several important tumor types. These include childhood leukemia, adult leukemias and lymphomas, as well as testicular and trophoblastic tumors. The addition of high-dose chemotherapy with growth factor and hemopoietic stem cell support has increased clinical remission rates even further. For the majority of patients with some of the more common malignancies, however, palliation (rather than cure) is still the most realistic goal of...
Over the last several decades, the introduction of new chemotherapeutic drugs and drug combinations has resulted in increased long term remission rate...
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cena:
642,77 zł |
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Biosimulation in Drug Development
ISBN: 9783527316991 / Angielski / Twarda / 540 str. This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms.
Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation of cells and tissues, as well as simulating drug action and effect. A further section is devoted to simulating networks and populations, and the whole is rounded off by a look at the potential for biosimulation in industrial... This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary to...
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cena:
1028,07 zł |
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Drugs Protocols Prehospital Emerg Care
ISBN: 9780867202144 / Angielski / Miękka / 476 str. |
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cena:
227,35 zł |
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Fundamentals of Medicinal Chemistry
ISBN: 9780470843079 / Angielski / Miękka / 302 str. Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style.
The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product. ...Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style.
The title begins ... |
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cena:
181,70 zł |
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