The presence of carotenoids in the diet and their role in human health has become a subject of unprecedented interest. The chapters in this book represent an account of the information presented at a recent workshop, combined with several additional invited contributions to cover topics more completely that are currently at the cutting edge of research. Some of the highlights of this book include a thorough review of the special role that vitamin A intake plays in the health status of developing countries, the essential role of vitamin A in cell signaling, the molecular targets involved in...

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the second of three volumes on hydrogen peroxide and cell signaling, and includes chapters on such topics as the cellular steady-state of H₂O_2, evaluating peroxiredoxin sensitivity towards inactivation by peroxide substrates, and peroxiredoxins as preferential targets in H2O2-induced signaling.

• Continues the legacy of this premier serial with quality chapters authored by leaders in the...

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the first of three volumes on hydrogen peroxide and cell signaling, and includes chapters on such topics as photooxidation of amplex red to resorufin, boronate-based fluorescent probes, and visualization of intracellular hydrogen peroxide with HyPer.

• Continues the legacy of this premier serial with quality chapters authored by leaders in the field
• Covers hydrogen peroxide and cell signaling
• Contains...

Despite the progress being made by researchers, Alzheimer s disease, along with other age-related neurodegenerative disorders, continues to exact a tremendous toll on our society. However, we are beginning to see a relationship that ties degenerative disorders to oxidative stress and lifestyle, suggesting the possibility for prevention and intervention through changes of individual habits, especially with regard to diet.

Oxidative Stress and Age-Related Neurodegeneration brings together expert researchers involved with recent developments across a variety of fields. In looking at...

Revised and expanded, this blue-ribbon reference emphasizes the latest developments in the identification, utilization, and analysis of flavonoids for the prevention of disease and maintenance of good health. The book examines the processes involved in the absorption, metabolism, distribution, and excretion of these compounds and the impact of biotransformation on flavonoid function.The Second Edition contains new discussions on the potential of dietary flavonoids to attenuate neurological dysfunction and degeneration, developments in gene expression and genomics for identification of...

Emphasizes the efficacy of synthetically occurring compounds in the management of free radical-mediated illnesses. The text details the design, development and delivery of therapeutic antioxidants used in the treatment of pathophysiological disorders, from amylotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) to Alzheimer's disease.