Patients' failure to complete a simple prescription course presents a tremendous public health problem and a considerable challenge for practicing clinicians. For those with chronic mental illnesses, non-adherence is an even greater problem than in other patient populations and substantially lowers the possibility of improvement or recovery. Additionally, adherence to treatment is further undermined by impairments in insight that often accompany mental illness. Much has been written about non-adherence across medical specialties. Yet, the topic of non-adherence in psychiatric patients is so...

A major shift in approaching Schizophrenia has been witnessed among psychiatrists with the belief now that early diagnosis and intervention may have a positive influence on the outcome of schizophrenia. The search for key diagnostic clusters to enhance early diagnosis is underway as well as concerted efforts to find biomarkers of disease and disease progression. To address this, this issue of the Psychiatric Clinics of North America presents distinguished academic clinicians and neuroscientists who provide comprehensive overviews of the present state of knowledge on the epidemiology, early...