The hallmark of insulin resistance is an obstacle to glucose uptake, resulting in hyperglycemia and hyperinsulinemia as well as type 2 diabetes mellitus. The prevalence of diabetes mellitus is rapidly increasing worldwide and is becoming an important health problem. In this book, the authors present current research in the study of insulin resistance including: the pathophysiological basis for antioxidant therapy of insulin resistance; new insight into the regulation of insulin resistance; burn injury and its association with insulin resistance and hyperglycemia which complicates clinical...

From the chalky horse-pills of faceless pharmaceutical conglomerates to the hot toddy that was Grandmother's remedy for bruised knees, broken hearts and everything besides, here are stories about the ways we face our ailments and the ways we seek to cure ourselves. Rose Tremain contributes an extract from Merivel, a follow-up to her award-winning Restoration; Alice Munro writes a haunting, beautiful memoir about a strange phase in her childhood; Gish Jen tells a story about two brothers who are fixing up a house . . . but can't quite fix up the ageing parents who will live in it. The issue...

Policeman-turned-detective-turned-writer A Yi describes life as a provincial gumshoe in China. Physician Siddhartha Mukherjee visits a government hospital in New Delhi, where he meets Madha Sengupta, at the end of his life and on the frontiers of medicine. Robert Macfarlane explores the limestone underworld beneath the Peak District. And Haruki Murakami revisits his walk to Kobe in the aftermath of the 1995 earthquake. In this issue - which includes poems by Charles Simic and Ellen Bryant Voigt, a story by Miroslav Penkov and non-fiction by David Searcy, Teju Cole and Hector Abad - Granta...

As a major contribution to the field of postgraduate activity in drama, theater, and performance, this resource identifies the essential characteristics of practice-based research across a range of countries, contexts, forms, and applications. A vital theory-based guide to such study, topics include locating practice-based research within historical, aesthetic, and educational settings; challenging received ideas of dramatic practice as thesis; distinguishing research from reflection and feelings from findings; and pushing practice-based research into new areas of critical inquiry. The...

When research is so connected to personal interest, experience, and familiarity that objectivity becomes a moveable feast, the line between documentation and invention blurs to near-invisibility. John Freeman asks what it means to locate oneself into research findings and narrative reports, and what happens when one's self goes further and becomes the research. Subjecting received truths to a series of hard questions, readers are taken on a journey through self-performance, traumatic memoir, the lure of weasel words, emotional evocation, the vagaries of memory, creative nonfiction, cultural...