Uterine fibroids (UFs) are benign masses that develop from the smooth muscle cells and connective tissue of the wall of the uterus under the influence of genetic and / or hormonal stimuli. These benign tumors are postulated to arise from a single, genetically altered, mesenchymal cell under the influence of gonadal hormones namely progesterone and 17d"-estradiol. The annual societal cost for fibroids is estimated up to 34 billion dollars, calculated through combined expenditures for medical management of symptomatic fibroids, lost work attributable to diagnosis of fibroids, and obstetrical...
Uterine fibroids (UFs) are benign masses that develop from the smooth muscle cells and connective tissue of the wall of the uterus under the influence...