Atrial fibrillation is a common supraventricular arrhythmia characterized by rapid and irregular atrial activation without a clear P-wave on an electrocardiogram. New Research on Atrial Fibrillation and Ischemic Heart Disease begins by discussing the risk factors, symptoms, and treatment of atrial fibrillation. Following this, the authors review the recently established relationship of atrial fibrillation with endurance sports activities in middle-aged athletes, connecting findings from various evidence in order to investigate this phenomenon since the pathophysiology of atrial fibrillation...