This book is a pivotal textbook for those considering, undertaking or appraising an evidence synthesis based on IPD for clinical research, especially those interested in intervention effects, modifiers of treatment response, identification of risk or prognostic factors, and the development and validation of risk prediction models. It covers all the key concepts and stages of a systematic review and meta-analysis of IPD, focusing primarily on the synthesis of randomised trials, as well as specialist topics, such as risk prediction, observational studies and advanced statistical methods. ...
This book is a pivotal textbook for those considering, undertaking or appraising an evidence synthesis based on IPD for clinical research, especially ...