This will be a substantial revision of a highly regarded text, intended for senior design capstone courses within departments of biomedical engineering, bioengineering, biological engineering and medical engineering, worldwide. Each chapter will be thoroughly updated and revised to reflect the latest developments. New material will be added on entrepreneurship, bioengineering statistics, clinical trials and CRISPR. New examples, applications and problems will be added in each chapter.There will be strong efforts made to increase the number of clinical applications to enhance the overall...