The aim of Volume 11 is to provide evidence on the indicators of fluid distribution and cellular integrity evaluated by nioelectrical impedance analysis in athletes of different performance levels and non-athletes. The second chapter presents a specific examination of the aryl hydrocarbon receptor among xenobiotic receptors, with a commentary on the preventive and therapeutic abilities of lignans against various diseases associated with the aryl hydrocarbon receptor signaling pathway, including cancers, teratogenesis, inflammatory bowel diseases, osteoarthritis, metabolic syndrome and...

Advances in Health and Disease. Volume 13 begins by examining how lipid abnormalities in chronic kidney disease attract continuous attention due to their unclear involvement in chronic kidney disease patient outcomes. If kidney function declines, inflammation and oxidative stress progress and lipid disturbances develop, and malnutrition may ameliorate dyslipidemia in advanced chronic kidney disease. Although rare, pancreatic trauma can significantly impact the life of a patient, with some requiring a total pancreatectomy which will result in pancreatogenic diabetes. Diagnosis can be...

Obesity worldwide represents a public health problem, compromising life expectancy in children and adolescents, and has been associated with mortality and a higher risk of developing non-alcoholic fatty liver disease. Advances in Health and Disease. Volume 17 investigates the association of adiponectin concentration with metabolic and inflammatory profiles of adolescents with obesity and diagnosis of non-alcoholic fatty liver disease. Non-alcoholic fatty liver disease is considered the hepatic manifestation of obesity, metabolic syndrome and type 2 diabetes mellitus, where the main toxic...

Advances in Health and Disease. Volume 14 opens with a chapter on Zika Virus, a ribonucleic acid virus of the Flaviviridae family, genus Flavivirus, Spondweni group, Zika species, isolated for the first time in 1947 from a primate in the Zika Forest in Uganda, a natural reserve near Entebbe. Next, the authors discuss multiple myeloma, which is characterized by the expansion of monoclonal plasma cells in the bone marrow. In about 95% of cases, the aberrant plasma cells produce a monoclonal immunoglobulin called monoclonal component that can be considered a marker of the disease. Hyperbaric...

Volume 16 first discusses iliopsoas, is a complex musculotendinous unit that acts primarily as a hip flexor, but it is also involved in pelvic stability and trunk balance. Although iliopsoas disorders are one of the most common causes of anterior hip pain in young athletes and active people, tendinopathy may also be described in elderly patients after total hip replacement. The authors go on to discuss, Clostridium difficile infection (CDI), a significant enteric pathogen of public health concern that causes toxin-mediated diarrhea in humans. CDI is commonly reported among hospital...

Sickle cell disease is one of the most common monogenic diseases globally, and the first disease where the genetic etiology was defined. It is common in sub Saharan Africa, the Middle East and India. This collection explores the advantages of newborn screening for sickle cell disease. Following this, the authors assess the costs of using continuous subcutaneous insulin infusion therapy for type 1 diabetes treatment. Scientific evidence has shown improvement in glycated hemoglobin levels, and in the reduction of glycemic oscillations and hypoglycemia episodes when compared to multiple-dose...

Advances in Health and Disease. Volume 19 begins by exploring differential diagnosis, a compilation of diagnostic possibilities, typically through the medium of evaluation of the prior probability of a specific diagnosis, given a particular test result (so-called Bayesian analysis). The authors discuss corticosteroids which have become indispensable in the treatment of a number of dermatological conditions. The advancement of newer steroid molecules with their vast anti-inflammatory, anti-mitotic, immunosuppressive and vasoconstrictive actions has completely changed dermatology. This...

Advances in Health and Disease. Volume 20 begins by exploring the clinical aspects of cryosurgery including: indications, patient selection, contraindications, technique, complications, and post-treatment follow-up. The authors review available data on current and potential agents for the treatment of vitiligo, an acquired disorder of melanin pigmentation that affects approximately 0.5-2% of the population. The available data regarding the role of oral magnesium supplementation in the treatment of prediabetes and high blood pressure is also studied. The long-term safety of intravitreal...

Advances in Health and Disease. Volume 21 first addresses the negative consequences of polypharmacy in older adults, highlighting evidence-based approaches to decrease inappropriate prescribing. An overview of generic drugs in Brazil is provided based on an analysis of literature on the subject, as well as public data. The authors assess the significant role phytochemicals play in combatting coronary heart disease, chronic inflammation, cancer, diabetes, Alzheimer disease, and more. Also assessed in this compilation are the different pathways of NF-IB signaling in cell survival and...

This compilation opens with a discussion of tuberculosis, the leading cause of death from a single infectious agent. Widespread occurrence of drug-resistant tuberculosis and multidrug-resistant- tuberculosis poses a serious threat to global control efforts. The authors review the importance of sleep for healthy functioning, the role sleep plays in eating patterns and diet, and how this may relate to weight gain and obesity. Diabetic cardiomyopathy, one of the major complications of type 2 diabetes mellitus, is studied. This condition is characterized by structural and functional changes in...