Using an evidence-based perspective and key concepts from the Occupational Therapy Practice Framework, this guideline provides an overview of the occupational therapy process for individuals with autism spectrum disorder (ASD), the prevalence of which is increasing rapidly in the United States. It defines the occupational therapy domain, process, and interventions-including sensory integration and sensory-based interventions, relationship-based interventions, school-based programs, social skills interventions, and comprehensive behavioral interventions-that occur within the boundaries of...