Up to 40% of new chemical entities discovered by the pharmaceutical industry today are poorly soluble or lipophilic compounds. The solubility issues complicating the delivery of these new drugs also affect the delivery of many existing drugs. Poorly water-soluble drugs show unpredictable absorption, since their bioavailability depends upon the dissolution in the gastrointestinal tract. The dissolution characteristics of poorly soluble drugs can be enhanced by several methods. Among these methods, solid dispersions (SDs) and cyclodextrins (CDs) have been extensively studied to improve...

Discussing all aspects connected with the scientific analysis of Rhipicephalus microplus, this book covers tick classification and identification, as well as methods of extracting natural products effective against ticks. It also describes tick cell culture procedures, tick acaricide-resistance diagnostics, and the identification of tick parasites and microorganisms from the host and the ticks' fluids, as well as the diagnosis of Babesia and Anaplasma in R. microplus.