Several poetic and prose compositions in early Italian literature contain references to the bubonic plague and other illnesses that were used in the language both literally and metaphorically. The first detailed description of a plague epidemic, however, was written by Giovanni Boccaccio in the introduction to The Decameron. It is a precise and dramatic view of the physical, social, and medical conditions of Florence during the epidemic of 1348. The Theme of the Plague in Italian Letters follows the subsequent developments, both in poetic and prose works, until the time of the plague of Milan...