The goal in designing sustained release is reduce the frequency of dosing or to increase the effectiveness of the drug by localization at the site of action, reducing the dose required or providing the uniform drug delivery. The use of controlled release (CR) formulations offers many potential advantages such as, sustained blood levels attenuation of adverse effects and improved patients compliance. It is important especially in the case of antihypertensive agents, to maintain constant blood levels, as other wise, dose dumping may cause hypo tension and sub-therapeutical levels may cause...