An extensive literature assessment is done and it is obvious that the methods are accessible for Ranitidine. HPLC is very expensive instrument and are not available in every laboratory. While UV/Visible spectrophotometer is a common instrument of all pharmaceutical analytical laboratory. Spectrophotometric analysis methods available for Ranitidine are tedious, time consuming and not much sensitive in term of precision and accuracy. It becomes essential to develop new rapid and cost effective methods that spectrophotometric determination would be simple, accurate, precise and sensitive. The...

Optimization is of critical importance in engineering. Engineers constantly strive for the best possible solutions, the most economical use of limited resources, and the greatest efficiency. As system complexity increases, these goals mandate the use of state-of-the-art optimization techniques. In recent years the theory and methodology of optimization have seen revolutionary improvements. Moreover, the exponential growth in computational power, along with the availability of multicore computing with virtually unlimited memory and storage capacity, has fundamentally changed what engineers...