There is a strong relationship between cigarette smoking and the risk of cardiovascular events. Smoking influences negatively coagulation - fibrinolysis cascade at any level, although it acts primarily on those pathways that are most important for an effective clot formation: endothelium, platelets, and fibronogen.

This title addresses the role of passive smoking in causing the multiple aspects of cardiovascular damage under biochemical, physiological, pathological, clinical, epidemiological and statistic all aspects.