This book constitutes selected papers presented during the First International Conference on Bangabandhu and Digital Bangladesh, ICBBDB 2021, held in Dhaka, Bangladesh, in December 2021. Due to the COVID-19 pandemic the conference was partly held online. The 16 papers presented were thoroughly reviewed and selected from the 90 submissions. They present research in the areas of artificial intelligence, machine learning, image processing, blockchain technology, human-computer interaction, etc.