This book constitutes the refereed proceedings of the 15th Mexican Conference on Pattern Recognition, MCPR 2023, held in Tepic, Mexico, during June 21-24, 2023. The 30 full papers presented in this book were carefully reviewed and selected from 61 submissions. The papers are divided into the following topical sections: pattern recognition and machine learning techniques; deep learning and neural networks; medical applications of pattern recognition; language processing and recognition; and industrial applications of pattern recognition.