Twenty years ago, the idea that Alzheimer's disease (AD) involved any sort of inflammatory or immune component seemed implausible. Now, there are hundreds of laboratories world-wide that are pursuing basic research in this area, and multi-site clinical trials are underway. How this dramatic sea-change came about is made clear in this book, both through overviews of the field and through focused papers on specific topics of recent interest. Complement, cytokines and the complex host of other acute phase reactants are covered, as are summaries of many epidemiologic and clinical-pathological...

Job migration across international boundaries and jobless economic "recoveries" are the latest disruptions in the workplace's human equation. To help policy makers, employers and employees to address these issues, Divanna and Rogers propose a more rigorous approach to Human Capital. They point out that the emergence of stronger measures, management techniques and balance sheet valuations was a key enabler to the emergence of dynamic financial capital markets and international exchanges. This book puts forth a framework for measuring, managing and negotiating issues of human business value. It...

In the 1990s shareholder value was applied to all aspects of corporate strategy and management decisions as a result of intense competition, globalization, advances in technology, deregulation and the financial markets. As we enter the twentyfirst century the business environment is one of increasing creative destruction, where competitive advantage is much harder to sustain. Real Options, a type of advanced financial analysis, applies financial option theory to real assets and offers a strategic framework that recognizes the need for management flexibility and to leverage risk in this...

Updated and revised, the third edition frames strategy as delivering firm value in both the short and long term while maintaining a sustainable competitive advantage. These issues are examined through industry evolution, the rise of the information economy, financial analysis, corporate and quantitative finance, and risk management concepts.