Hepatitis C virus (HCV) infection is one of the most important Flavivirida infections with significant clinical problems throughout the world in humans. Six major Hepatitis C virus (HCV) genotypes and hundreds of subtypes have been identified globally. All these genotypes are generally studied for epidemiology, their vaccine development and clinical management. This thesis comments the frequency distribution of various HCV genotypes circulate in different areas/districts of Khyber Pakhtoonkhaw Province of Pakistan. Out of the tested samples, genotype specific PCR fragments were observed in...