In 1984 Desmond O'Connor and David Phillips published their comprehensive book Time-correlated Single Photon Counting." At that time time-correlated s- gle photon counting, or TCSPC, was used primarily to record fluorescence decay functions of dye solutions in cuvettes. From the beginning, TCSPC was an am- ingly sensitive and accurate technique with excellent time-resolution. However, acquisition times were relatively slow due to the low repetition rate of the light sources and the limited speed of the electronics of the 70s and early 80s. Moreover, TCSPC was intrinsically one-dimensional,...
In 1984 Desmond O'Connor and David Phillips published their comprehensive book Time-correlated Single Photon Counting." At that time time-correlated s...
Time-correlated single photon counting (TCSPC) is a remarkable technique for recording low-level light signals with extremely high precision and picosecond-time resolution. TCSPC has developed from an intrinsically time-consuming and one-dimensional technique into a fast, multi-dimensional technique to record light signals. So this reference and text describes how advanced TCSPC techniques work and demonstrates their application to time-resolved laser scanning microscopy, single molecule spectroscopy, photon correlation experiments, and diffuse optical tomography of biological tissue. It...
Time-correlated single photon counting (TCSPC) is a remarkable technique for recording low-level light signals with extremely high precision and pi...
