This volume constitutes the thoroughly refereed conference proceedings of the 25th International Conference on Industrial Engineering and Other Applications of Applied Intelligend Systems, IEA/AIE 2012, held in Dalian, China, in June 2012. The total of 82 papers selected for the proceedings were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on machine learning methods; cyber-physical system for intelligent transportation applications; AI applications; evolutionary algorithms, combinatorial optimization; modeling and support of...